Results 41 to 50 of about 31,263 (267)
From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care
Molecular Oncology, EarlyView.Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
π-EconomyThe article is devoted to the development of fundamental and applied aspects of indicative strategic programming, providing the formation of the organizational foundations of the cyber-information development of industry.
Babkin Aleksandr +2 more
doaj +1 more source
Journal of Aerospace Technology and Management, 2023 Public Science and Technology Institutions (STIs) need to assume and consolidate a proactive role in innovation management to transform knowledge advances into appropriate results for the industrial base.
Nestor Brandão Neto +2 more
doaj
Mettere in gioco i servizi ecosistemici: limiti e opportunità di nuovi scenari sociali ed economici
Ri-vista: Ricerche per la Progettazione del Paesaggio, 2015 Ecosystems are an irreplaceable support for a region’s quality of life, thanks to the goods and services that they provide (ecosystem services). These ecosystem services can be assessed in economic terms, considering the economic weight of natural ...
Riccardo Santolini +2 more
doaj +1 more source
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Cogent Business & Management, 2017 Media industry ecosystem has undergone major transformations due to emergence of disruptive innovations. When industry ecosystem incumbents have dynamic organizational capability and make necessary strategic changes, they could exploit disruptive ...
Masoud Gholampour Rad
doaj +1 more source
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Liang you shipin ke-jiIn order to understand the latest situation and future trends of the Australia food industry under the concept of sustainability development, we have overviewed the circumstances of food safety and waste in Australia, the impact of food industry on ...
TAN Hong-zhuo +2 more
doaj +1 more source