Results 31 to 40 of about 4,476,910 (292)

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Assessing the risk of environmental pollution caused by tourism activities (recreation – sports) in natural environments of Shahrood County

Anthropogenic Pollution, 2020
The purpose of this study is to identify environmental pollution caused by tourism activities in Shahrood county and environmental risk assessment. In the first step, tourism sites (recreational-sports) in the study area were identified. In the next step,
Sepideh Hosseini Dinani, Seyed Mostafa Tayebi Sani, Bagher Morsal, Ali Fahiminejad   +3 more
doaj   +1 more source

The Concept of Using the Strategic Noise Maps in Planning of Urban Space in Poland [PDF]

Journal of Civil Engineering and Architecture, 2013
In the territory of Poland the manner of urban space management is defined by a planning document called LLUP (local land use plan). When analyzing the development process of Polish cities, an obvious conclusion emerges about the lack of complex studies and researches of the environment concerning the issue of acoustic climate.
null Kinga Szopińska, null Janusz Kwiecień   +1 more
openaire   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Citizens’ exposure to predominant noise sources in agglomerations

Noise Mapping
Environmental noise directive requires Member States to produce and periodically update strategic noise maps for agglomerates in order to evaluate citizens’ noise exposure before the action plan.
Bolognese Matteo, Fredianelli Luca, Stasi Gianmarco, Ascari Elena, Crifaci Giulia, Licitra Gaetano   +5 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Truk Islands : special strategic map

, 1945
Scale 1:1,000,000 ; Lambert conformal conic projection. 1 map : color ; 46 x 68 cm. First edition-AMS 1. Prepared under the direction of the Chief of Engineers, U.S. Army ; compiled by the Army Map Service, February 1943. Standard map series designation:
United States. Army Map Service.
core   +1 more source

Noise pollution maps in the perimeter of Galati main ports

Annals of "Dunărea de Jos" University of Galaţi: Fascicle XI Shipbuilding, 2017
Noise mapping is one of the modern methods of evaluation of urban acoustic pollution due to the presence of road traffic, rail traffic (train or tram), industrial noise and air traffic.
Costică Hogaș, Alin Pohilca, Costel Iulian Mocanu   +2 more
doaj