Results 71 to 80 of about 12,499 (278)

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

A Stochastic Simulation Framework for the Prediction of Strategic Noise Mapping and Occupational Noise Exposure Using the Random Walk Approach

PLOS ONE, 2015
Strategic noise mapping provides important information for noise impact assessment and noise abatement. However, producing reliable strategic noise mapping in a dynamic, complex working environment is difficult. This study proposes the implementation of the random walk approach as a new stochastic technique to simulate noise mapping and to predict the ...
Lim, Ming Han, Haron, Zaiton, Yahya, Khairulzan, Abu Bakar, Suhaimi, Dimon, Mohamad Ngasri   +4 more
openaire   +5 more sources

T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ± 
Sarah J. Wright, Scotty G. McKay, Jean Ramos Bou, Fen Bao, Vivian B. Truong, Chenyang Li, Li Jiang, Anza B. Memon, E. Mark Haacke, Yulin Ge, Yongsheng Chen   +10 more
wiley   +1 more source

CFAR-DP-FW: A CFAR-Guided Dual-Polarization Fusion Framework for Large-Scene SAR Ship Detection

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Effective ship detection in synthetic aperture radar (SAR) imagery is crucial for maritime safety and surveillance. Despite the advancements in deep learning for SAR ship detection, significant challenges remain, particularly in large scenes.
Tianjiao Zeng, Tianwen Zhang, Zikang Shao, Xiaowo Xu, Wensi Zhang, Jun Shi, Shunjun Wei, Xiaoling Zhang   +7 more
doaj   +1 more source

Agglomeration noise strategic maps in Catalonia

, 2010
The Directive 2002/49 on evaluation and management of the environmental noise demands in case of agglomerations, a series of information that one must communicate to the Commission, between which there is the number of people whose housings are exposed to every range of values of Lden and Lnight in dBA.
Jiménez Diaz, Santiago, Romeu Garbí, Jordi, Pàmies Gómez, Teresa, Majó, Maite   +3 more
openaire   +1 more source

Does Long‐Term Lower Extremity Strength Training in Adults With Knee Osteoarthritis and Varus Alignment Reduce Knee Joint Loading During Gait?

Arthritis Care &Research, EarlyView.
Objective We examined whether 18 months of strength training in individuals with knee varus alignment and medial tibiofemoral osteoarthritis (OA) reduced knee joint loads during walking compared to an attention control group. Methods This study was a secondary analysis of a randomized clinical trial that compared the effects of strength training to a ...
Stephen P. Messier, Matthew N. Vigliotti, Paige E. Rice, Brian Pietrosimone, Shannon L. Mihalko, Edward H. Ip, Richard F. Loeser, David J. Hunter, Ali Guermazi, Ryan Hill, Santiago Saldana, Kim L. Bennell, Paul DeVita   +12 more
wiley   +1 more source

Decoupling Visual Saliency from Decision Logic: A Fidelity Evaluation of DAAM in Vision Transformers

Applied Sciences
Vision Transformers (ViTs) have achieved remarkable success; however, their internal decision-making mechanisms remain largely opaque. The Dynamic Accumulated Attention Map (DAAM) has emerged as a prominent interpretability tool that visualizes model ...
Ying Zhan, Xianfeng Li
doaj   +1 more source

Levels of noise pollution in North East and North Cumbria Integrated Care System (ICS) during nighttime and 24-hour periods based on data from strategic noise mapping. An interactive map application

ACCESS THE INTERACTIVE MAP VIA RELATED URLS AT THE BOTTOM OF THIS RECORDLevels of Noise Pollution in North East and North Cumbria Integrated Care System (ICS) during Nighttime and 24-Hour Periods Based on Data from Strategic Noise Mapping. An Interactive
Tsakiridi, Anastasia, Tsimpida, Dialechti   +1 more
core   +1 more source

Discordance Between Systemic Lupus Erythematosus Disease Activity Index Domain Weights and Their Association With Organ Damage Accrual

Arthritis Care &Research, EarlyView.
Objective Studies of damage accrual in patients with systemic lupus erythematosus (SLE) show associations with disease activity measured by the SLE Disease Activity Index 2000 (SLEDAI‐2K), but these associations are imperfect. SLEDAI scores are powerfully influenced by weightings (1–8) assigned to each domain.
Kevin Zhang, Eric F. Morand, Sarah E. Boyd, François Petitjean, Alberta Hoi, Rachel Koelmeyer, Iolanda Miceli, Julie A. Monk, Hieu T. Nim   +8 more
wiley   +1 more source

A Q‐Learning Algorithm to Solve the Two‐Player Zero‐Sum Game Problem for Nonlinear Systems

International Journal of Adaptive Control and Signal Processing, Volume 39, Issue 3, Page 566-581, March 2025.
A Q‐learning algorithm to solve the two‐player zero‐sum game problem for nonlinear systems. ABSTRACT This paper deals with the two‐player zero‐sum game problem, which is a bounded L2$$ {L}_2 $$‐gain robust control problem. Finding an analytical solution to the complex Hamilton‐Jacobi‐Issacs (HJI) equation is a challenging task.
Afreen Islam, Anthony Siming Chen, Guido Herrmann   +2 more
wiley   +1 more source