Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
FEBS Open Bio, EarlyView.In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
The 6G integrated perception and networking technology enables the low-altitude economy to achieve carbon neutrality: Dynamic sleep strategy for eVTOL wireless charging based on time-energy-carbon coupling. [PDF]
PLoS OneChen H, Wang X, Yuan L, Gong J.
europepmc +1 more source
Avignon and Paris sketchbook [picture] /
, 1930 Title devised by cataloguer.; Part of the John Power sketchbooks collection.; Inscriptions: "Avignon + Paris"--In pencil on front cover.; Condition: Yellowing, soiled, stained.; Also available online at: http://nla.gov.au/nla.pic-vn6292743; Exhibited ...
Power, J. J. W. (John Joseph Wardell), 1881-1943.
core
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
FEBS Open Bio, EarlyView.Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
A Service Held Together in Practice: A Qualitative Study of Interorganizational Collaboration in a Swedish Youth Mental Health and Substance Use Service. [PDF]
Int J Ment Health NursKihlström J +3 more
europepmc +1 more source
Miscellaneous sketchbook, 2 [picture] /
, 1930 Title devised by cataloguer from acquisitions documentation.; Part of the John Power sketchbooks collection.; Condition: Yellowing, soiled, stained, tears.; Also available online at: http://nla.gov.au/nla.pic-vn6293848; Exhibited: Abstraction-Creation: J.
Power, J. J. W. (John Joseph Wardell), 1881-1943.
core
Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
FEBS Open Bio, EarlyView.We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source
CPA governance restructuring and section autonomy: a case study in organizational resistance to structural diversity. [PDF]
Int J Ment Health SystFaber SC +3 more
europepmc +1 more source
Norfolk sketchbook [picture] /
, 1930 Title devised by cataloguer.; Part of the John Power sketchbooks collection.; Inscriptions: "Norfolk"--In pencil on front cover.; Condition: Yellowing, soiled, stained.; Also available online at: http://nla.gov.au/nla.pic-vn6292751; Exhibited ...
Power, J. J. W. (John Joseph Wardell), 1881-1943.
core
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source