COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Adolescents' Strategies to Manage Mental Health Challenges In and After the Pandemic: Two Mixed-Methods Studies. [PDF]
Huizenga HM +4 more
europepmc +1 more source
Rhetorical strategies of Teresa de Cartegena and Sor Juana Ines de la Cruz
Margaret Russell Ewalt
openalex +1 more source
A Study of Block Scheduling and Instructional Strategies and their Influence on Algebra Achievement in Classrooms Throughout North Central Texas [PDF]
Melissa Sue McClure
openalex +1 more source
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Learning strategies, study behaviors, and academic performance among medical students in Jordan: A cross-sectional study. [PDF]
Mahmoud WA +8 more
europepmc +1 more source
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
How to Design and Implement a Structured Curriculum in Health Professions Education: A Nine-Step Framework Building on Kern's Approach. [PDF]
Escourrou É, Oustric S.
europepmc +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Health improvement and inequality in local authority green infrastructure strategies in England: a policy review. [PDF]
Hands A +5 more
europepmc +1 more source

