Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Letter by Sharma et al Regarding Article, “Impact of the Presence and Extent of Incomplete Angiographic Revascularization After Percutaneous Coronary Intervention in Acute Coronary Syndromes: The Acute Catheterization and Urgent Intervention Triage Strategy (ACUITY) Trial” [PDF]
, 2012 Abhishek Sharma +2 more
openalex +1 more source
Author response for "A Novel EphA4 Signaling‐Based Therapeutic Strategy for Osteoarthritis in Mice"
, 2021 Virginia M. Stiffel +4 more
openalex +1 more source
Progress in sustainment? Reflections on ongoing gaps and opportunities for the field of implementation science in response to Dopp et al., 2025. [PDF]
Implement SciShelton RC, Sichel CE.
europepmc +1 more source
Cost recovery strategies for public sector Botanic Gardens [PDF]
, 2005 Wei Har Wong
openalex +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Conversation Barriers and Strategies Used by People With Parkinson's and Their Partners to Support Conversation. [PDF]
Int J Lang Commun DisordThilakaratne R +3 more
europepmc +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
A longitudinal psychological model of writing development: interactions among self-efficacy, regulation, and anxiety. [PDF]
Front PsycholCheng S, Lin C, Wei D, Chen Y.
europepmc +1 more source