Results 111 to 120 of about 1,652,823 (301)

Something is rotten in development’s garden: Neglectings, barriers and opportunities for engaging with difference in the co-creation of strategies for change [PDF]

open access: yes, 2015
Acknowledging that development initiatives often fail to bring about the long-lasting changes envisioned, the concept of ‘participation’ has been promoted to support principles such as ownership and sustainability. Unfortunately, participatory approaches
Andersson, Catherine
core  

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Adaptation strategies of winegrowers to climate change: Comparison of Languedoc Roussillon (France) and Tuscany (Italy) wine regions

open access: yesNew Medit
The relationship between wine products and the concepts of quality, identity, place, typicality and terroir is rooted in a deep socio-cultural and agricultural connection.
Giacomo Inserra   +2 more
doaj   +1 more source

A Strategy for Change

open access: yesAl-Raida Journal, 1970
The following article is an abridged version of a piece written by Marilee Karl for ISIS, an International Women's Information and Communication Service. It was published in 1983 (p.189) in their Resource Guide for Organization and Action. 
openaire   +1 more source

All the right moves: why in utero transfer is both important for the baby and difficult to achieve and new strategies for change. [PDF]

open access: yesF1000Res, 2020
Watson H   +8 more
europepmc   +1 more source

Business Intelligence: towards a new concept in economic analysis? (In French) [PDF]

open access: yes
Two questions are the core of business intelligence: coordination and cooperation. Both, coordination and cooperation, are simultaneously resources and the result of strategies of change.
Gabriel COLLETIS (LEREPS-GRES)
core  

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

open access: yesFEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy