Results 61 to 70 of about 1,652,823 (301)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Os movimentos sociais rurais “alternativos” em Moçambique e suas estratégias de mudança

open access: yes, 2022
Over the last decade rural conflicts in Mozambique suffered an acceleration, due to large land investments by foreign subjects, especially in the central and northern parts of the country.
Bussotti, Luca
core   +3 more sources

Strategies of change

open access: yes, 1976
Meeting: Meetings on Reshaping the International Order, Dec. 1974-June 1976, Rotterdam, NLIDRC governor. Essay on strategies of planned change for a New International Economic Order - discusses decision making at the international, regional and national ...
Brucan, S., Thorsson, I., Urquidi, V.L.
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

The normality and materiality of the dominant discourse: Voluntary work inside a Dutch asylum seeker center

open access: yes, 2016
This article explores the narratives of the volunteers working inside Dutch asylum seeker centers (AZCs). The objective was to explore the challenges and coping strategies of these volunteers, who face contradictory processes: being engaged to improve ...
Larruina, R.L.   +3 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

British diversity professionals as change agents - radicals, tempered radicals or liberal reformers?

open access: yes, 2007
This paper explores the role of diversity professionals involved in the development and implementation of organizational equality and diversity policy.
Deborah Dean   +5 more
core   +1 more source

Decolonizing Social Work Education Through Indigenous Family-Based Research

open access: yes, 2022
Family-based research is an Indigenous methodology that engages the self, family, and relationships as important sites of resistance and resurgence.
King, Jennifer
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Keynote to Nordic Environmental and Sustainability Education Conference 2025 :Don't Panic! And a few other principles for environmental & sustainability educators in case of authoritarian extractivism [PDF]

open access: yes
Keynote speech on principles for environmental and sustainability educators in changing political climates. The speech proposes 8 principles: 1: Don’t Panic, you are not alone 2: Deal with your own fears first3: Find allies and make connections4: Work ...
Facer, Keri
core   +1 more source

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