Results 101 to 110 of about 4,780,543 (332)

HOW MIDDLE MANAGERS CONTRIBUTE TO STRATEGY FORMATION PROCESS: CONNECTION OF STRATEGY PROCESSES AND STRATEGY PRACTICES

RAE: Revista de Administração de Empresas, 2010
The role of middle management is essential when managing integrative and emergent strategy formation processes. We stand out the importance of its role connecting micro and macro organizational level offering a very important contribution when examining ...
Fernando Juan Peris-Bonet, María Teresa Canet-Giner, Rosalia Aldraci Barbosa Lavarda, Rosalia Aldraci Barbosa Lavarda, María Teresa Canet-Giner, Fernando Juan Peris-Bonet   +5 more
doaj  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Contornando o Estigma: uma análise dos estúdios de tatuagens em Belo Horizonte

Teoria e Prática em Administração, 2014
Small businesses are vital to the economy, contributing to PIB and to job creation. Howerver, most part of these businesses have difficult to survive, what reveals problems in theirs managament processes.
Silva, Alexsandra Nascimento da, Saraiva, Luiz Alex Silva   +1 more
doaj  

Open Innovation and Open Strategy from the perspective of Strategy as Practice: a theoretical essay

Revista Eletrônica de Ciência Administrativa
Open Strategy (OS) has emerged as a phenomenon that has allowed organizations to adapt to the concept that incorporates Open Innovation (OI) practices with a focus on greater transparency and inclusion in strategy formation processes.
Maria Luciana Trigos, Rosalia Aldraci Barbosa Lavarda   +1 more
doaj   +1 more source

Taking Goffman seriously: Developing Strategy-as-Practice [PDF]

Critical Perspectives on Accounting, 2018
As yet, there has been no systematic exposition of the whole of Goffman’s work in its significance for strategy and strategic management. This paper aims to fill this gap by providing a more wide-ranging treatment of Goffman’s central ideas that goes beyond some of the more widely circulated core notions, such as frontstage/backstage and facework.
openaire   +3 more sources

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Strategy Workshops and Strategic Change [PDF]

Despite the attention that strategic change as a topic of research has received, there remain considerable difficulties in conceptualizing the actual sources of strategic change.
MacIntosh, Robert, MacLean, Donald, Seidl, David   +2 more
core