Results 111 to 120 of about 6,776,213 (311)

Developing a strategy for “battleship”

Mathematical and Computer Modelling, 1988
Rodin, E. Y., Cowley, J., Huck, K., Payne, S., Politte, D.   +4 more
openaire   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

The impact of built environment on urban residents’ cycling intensity and its heterogeneity: A case study of the central urban area of Wuhan

Journal of Urban Management
Urban cycling emerges as a sustainable transportation mode with demonstrated potential to alleviate traffic congestion, mitigate air pollution, and improve public health outcomes.
Wei Wei, Wenyi Xu, Mengyao Hong, Junnan Xia   +3 more
doaj   +1 more source

Assessment and strategy development for SARS-CoV-2 screening in wildlife: A review. [PDF]

Vet World, 2023
Italiya J, Bhavsar T, Černý J.
europepmc   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Machining strategy development in 5-axis milling operations using process models [PDF]

, 2010
Increased productivity and part quality can be achieved by selecting machining strategies and conditions properly. At one extreme very high speed and feed rate with small depth of cut can be used for high productivity whereas deep cuts accompanied with ...
Budak, Erhan, Murtezaoglu, Yavuz, Murtezaoğlu, Yavuz, Ozkirimli, Omer Mehmet, Ozturk, Erdem, Tunc, Taner L., Tunç, Taner L., Özkırımlı, Ömer Mehmet, Öztürk, Erdem   +8 more
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Immunomodulatory roles of selenium nanoparticles: Novel arts for potential immunotherapy strategy development. [PDF]

Front Immunol, 2022
Chen G, Yang F, Fan S, Jin H, Liao K, Li X, Liu GB, Liang J, Zhang J, Xu JF, Pi J.   +10 more
europepmc   +1 more source

EU Strategies and the Role of Education for Sustainable Development [PDF]

In June 2006 the European Union decided upon a new Strategy for Sustainable Development. Together with the Lisbon Strategy that was revised in 2005, there is now some coherence between the two strategies which had been conflicting before.
Anca Gabriela TURTUREANU, Cornelia Elena TUREAC   +1 more
core