Results 111 to 120 of about 3,218,936 (303)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

To Merge or not to Merge: That is the question [PDF]

open access: yes, 2000
In this paper we analyze the implementation of socially optimal mergers when the regulator is not informed about the parameters that determine social and private gains from potential mergers.
Corchón, Luis C., Faulí-Oller, Ramón
core   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

The preparatory phase for ground larviciding implementation for chocerciasis control in the Meme River Basin in South West Cameroon: the COUNTDOWN Consortium alternative strategy implementation trial. [PDF]

open access: yesParasit Vectors, 2022
Ekanya R   +14 more
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Impact of middle managers’ competencies on strategy implementation in Vietnamese enterprises: a multilevel strategy approach

open access: yesCogent Business & Management
This research investigates the impact of constituent factors shaping the competencies of middle-level managers on the implementation of strategies and assesses variations in the influence of these factors on strategy implementation across enterprise and ...
Van Nguyen Thi   +2 more
doaj   +1 more source

Canadian High School Rugby Coaches Readiness for an Injury Prevention Strategy Implementation: Evaluating a Train-the-Coach Workshop. [PDF]

open access: yesFront Sports Act Living, 2021
Shill IJ   +9 more
europepmc   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

Evaluation of the Strategy Implementation Obstacles in Tourism Industry [PDF]

open access: yesMuṭāli̒āt-i Mudīriyyat-i Gardishgarī, 2014
The tourism policymaking formulated through tourism development acts and national and/or regional comprehensive plans, is an important tool for strategic development of tourism. However, challenges in the execution phase often hinder attaining the stated
Nader Mazloom Mazloom, Seyed Jalali
doaj  

Secure Implementation: Strategy-Proof Mechanisms Reconsidered [PDF]

open access: yes
Strategy-proofness, requiring that truth-telling is a dominant strategy, is a standard concept in social choice theory. However, the concept of strategy-proofness has serious drawbacks. First, announcing one's true preference may not be a unique dominant
Saijo, Tatsuyoshi   +2 more
core  

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