Results 41 to 50 of about 3,162,143 (211)
Almost-dominant Strategy Implementation [PDF]
Though some economic environments provide allocation rules that are implementable in dominant strategies (strategy-proof), a significant number of environments yield impossibility results.
James Schummer
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Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
The Involvement of Boards in Strategy Implementation [PDF]
The classical management perspective works on the assumption that CEO can design an explicit “grand strategy” for the entire enterprise. Later strategy perspectives question these normative assumptions and depict strategy as a messy, disorderly and ...
Anca BORZA +2 more
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The Implementation of Kwl Strategy to Improve Students Reading Comprehension on Analytical Exposition Text [PDF]
, 2013 The purpose of conducting this research was to improve students reading comprehension on identifying the information given in arguments from analytical exposition text by using know-want-learn as a strategy of learning.
Arifin, Z. (Zainal) +2 more
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Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Networking lifelong learning: making it happen, an implementation plan [PDF]
, 1999 Presented by the FEILT committee Chair - Jenny Scribbins In April 1999 the Council’s FEILT committee (FEILTC) published its proposal information learning technology (ILT) development strategy for the sector entitled Networking Lifelong Learning.
core
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Orchestration of the Marketing Strategy under Competitive Dynamics [PDF]
Constructing suitable marketing strategy and implementing it effectively is an art and science both like orchestration of a symphony. The discussion in this paper blends this analogy with the science of marketing demonstrating the levels of strategy ...
Rajagopal
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