Results 181 to 190 of about 8,149,283 (401)

WATER RESOURCES DEVELOPMENT IN AFRICA: A REVIEW AND SYNTHESIS OF ISSUES, POTENTIALS, AND STRATEGIES FOR THE FUTURE [PDF]

open access: gold, 1997
Mark W. Rosegrant   +3 more
openalex   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Strategy of directions, forms and tools of state influence on development processes of the regional business environment

open access: gold, 2023
Олександр Черняєв   +2 more
openalex   +2 more sources

Consequential urban development of sustainable strategies

open access: yesUrban Geography
A green transition is necessary for urban development so that cities can foster a more sustainable urban future. While this need has gained increasing recognition in planning policies in recent decades, there is a risk that counterproductive interests, which are concealed by the sustainable agenda, may go unnoticed.
openaire   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

ARGUMENTATIVE STRATEGIES IN THE DEVELOPMENT OF CRITICAL THINKING SKILLS IN ENGINEERING STUDENTS

open access: bronze, 2023
Rómulo Cresenciano Romero Centeno   +3 more
openalex   +2 more sources

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