Molecular mechanisms of seed dormancy release in Paeonia lactiflora revealed through transcriptomic and metabolomic analysis. [PDF]
Mu Y +5 more
europepmc +1 more source
Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito +8 more
wiley +1 more source
Time to Screen for Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): Insights From a Single-Center Retrospective Risk Stratification Study in Saudi Arabia. [PDF]
Zahrani T, Rayyani AH, Gardezi SA.
europepmc +1 more source
Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang +4 more
wiley +1 more source
Response of supersaturated TDG distribution characteristics to thermal stratification in a cascading large deep reservoir. [PDF]
Wang H +7 more
europepmc +1 more source
A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort
ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi +17 more
wiley +1 more source
A Narrative Review of Syncope Decision Rules: A Case for Point-of-Care Cardiac Ultrasound for Cardiac Syncope. [PDF]
Situ-LaCasse E +4 more
europepmc +1 more source
ABSTRACT Objectives We aimed to determine the frequency of subclinical optic nerve (ON) lesions using MRI, optical coherence tomography (OCT), and visual evoked potentials (VEP) in radiologically isolated syndrome (RIS), and to assess their diagnostic and prognostic significance.
Christine Lebrun‐Frenay +13 more
wiley +1 more source
Response to "Refining the Predictive Role of T2-Weighted Imaging Features in Breast Cancer: A Hypothesis Linking Tumor Characteristics to Extreme Chemoresistance". [PDF]
Park VY, Youn I.
europepmc +1 more source

