Results 81 to 90 of about 873,763 (308)

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Population stratification and genetic association studies in South Asia [PDF]

, 2005
Population stratification and its influence on genetic association studies is a controversial topic. Although it has been suggested that stratification is unlikely to bias the results of association studies conducted in developed countries, convincing ...
Bittles, Alan, Bittles, A.H.
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

An Investigation of Meromixis in Cave Pools, Lechuguilla Cave, New Mexico. [PDF]

International Journal of Speleology, 2008
Chemical characteristics of permanent stratification in cave pools (meromixis) may provide insight into the geochemical origin and evolution of cave pool waters.
David B. Levy
doaj  

Occupations, workplaces or jobs?: An exploration of stratification contexts using administrative data [PDF]

, 2019
Avent-Holt D, Henriksen LF, Hagglund AE, et al. Occupations, workplaces or jobs?: An exploration of stratification contexts using administrative data. Research in Social Stratification and Mobility.
Kodama, Naomi, Folke Henriksen, Lasse, Rainey, Anthony, Melzer, Silvia Maja, Avent-Holt, Dustin, Mun, EunmiK, Jung, Jiwook, Hagglund, Anna Erika, Tomaskovic-Devey, Donald, Henriksen, Lasse Folke, Mun, Eunmi   +10 more
core   +1 more source

Case selection and stratification.

, 2021
Case selection and stratification.
Beatriz Martinelli Menezes Gonçalves (11864537), Agatha S. Rodrigues (11864543), Rossana Pulcinelli V. Franco (11864540)   +2 more
core   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Multivariable analysis after stratification.

, 2022
Multivariable analysis after stratification.
Mikihito Kajiya (177676), Tomoyuki Iwata (2483476), Haruya Ohno (120083), Shinya Sasaki (1588258), Kazuhisa Ouhara (352273), Yuta Hamamoto (9538457), Tsuyoshi Fujita (263131), Hidemi Kurihara (63613), Tomoaki Shintani (2476495), Noriyoshi Mizuno (3964448), Nao Komatsu (3964451), Shinji Matsuda (6062693), Tsuyoshi Miyagawa (12800172), Masayasu Yoneda (712071)   +13 more
core   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source