Results 21 to 30 of about 7,422 (216)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Introduction : time and space in the neoliberal university [PDF]

open access: yes, 2019
Time and Space in the Neoliberal University offers new interdisciplinary analyses of borders, boundaries, blockages and im/mobilities in higher education, and how these might be identified, inhabited, resisted, and re-worked.
Breeze, Maddie   +5 more
core   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Stratified (L,M)-fuzzy quasi-uniform spaces

open access: yes, 2010
In this paper, we introduce the notions of stratified (L,M)-fuzzy quasi-uniform spaces and (L,M)-fuzzy quasi-uniform bases, where L and M are completely distributive lattice and complete residuated lattice, respectively.
Abbas, S.E.
core   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Ellipsoidal vortices in rotating stratified fluids : beyond the quasi-geostrophic approximation

open access: yes, 2015
Support for this research has come from the UK Engineering and Physical Sciences Research Council (grant number EP/H001794/1).We examine the basic properties and stability of isolated vortices having uniform potential vorticity (PV) in a non-hydrostatic ...
Dritschel, David G., Tsang, Yue-Kin
core   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

Effect of Prandtl's ration on balance in geophysical turbulence

open access: yes, 2015
Support for this research has come from the UK Engineering and Physical Sciences Research Council (grant no. EP/H001794/1).The fluid dynamics of the atmosphere and oceans are to a large extent controlled by the slow evolution of a scalar field called ...
McKiver, William Joseph   +1 more
core   +1 more source

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