Results 211 to 220 of about 60,358 (297)

Armed Conflict and Penetrating Traumatic Brain Injury in Children in the Gaza Strip.

JAMA Netw Open
Asfa M, Stray Andreassen J, Khan AB, Stray Andreassen G, Matar MAK, Alaqad AAA, Nassar IZD, Albhnasawi MAJ, Salvesen ØO, Gulati S, Abuhadrous N.   +10 more
europepmc   +1 more source

Microscopic and molecular identification of <i>Toxocara cati</i> in domestic and stray cats in Al Diwaniyah Province, Iraq. [PDF]

Open Vet J
Jarad NI, Al-Bayati HH, Al-Shabbani AH, Shakir SS.   +3 more
europepmc   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Magnetic Composites for Advanced Characterization of Magnetic Field Sensors and Biosensors. [PDF]

Sensors (Basel)
Burban EA, Safronov AP, Il'inova KO, Melnikov GY, Svalov AV, Beketov IV, Yushkov AA, Kurlyandskaya GV.   +7 more
europepmc   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Bias-Engineered Synthetic Antiferromagnets Hosting Sub-20 nm Zero-Field Skyrmions at Room Temperature. [PDF]

Adv Sci (Weinh)
Darwin E, Tomasello R, Peremadathil Pradeep R, Carpentieri M, Finocchio G, Hug HJ.   +5 more
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Seroprevalence of Toxoplasma gondii and Feline Immunodeficiency Virus in Domestic Cats and Their Associations with Clinical Signs. [PDF]

Acta Parasitol
Bártová E, Sedlák K, Vodlan Š, Budíková M, Račka K.   +4 more
europepmc   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

First isolation and molecular confirmation of Brucella canis in dogs from Egypt. [PDF]

BMC Microbiol
Thabet A, Orabi A, Abdel-Hamid NH, El-Ebeedy LA, Kadry M, Hashad ME.   +5 more
europepmc   +1 more source