Results 191 to 200 of about 10,858,871 (318)

Artificial intelligence-assisted method of structural health monitoring of subway shield tunnel based on insulation degradation location. [PDF]

PLoS One
Zhao Y, Wang C, Tao Y.
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Reconfigurable Magnetic Inhibitor for Domain Wall Logic and Neuronal Devices. [PDF]

ACS Nano
Durner CA, Migliorini A, Jeon JC, Parkin SSP.   +3 more
europepmc   +1 more source

On stray currents in dynamo-machines

On stray currents in dynamo-machines
種別 ...
openaire  

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Measuring the Operating Condition of Induction Motor Using High-Sensitivity Magnetic Sensor. [PDF]

Sensors (Basel)
Kobayashi A, Nakamura K, Ono T.
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Dual-output hybrid converter based on the modular universal dc-ac/dc converter. [PDF]

Sci Rep
Gutiérrez-Escalona J, González-Antúnez JJ, Roncero-Clemente C, Matiushkin O, Pires VF, Romero-Cadaval E.   +5 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Field-resilient supercurrent diode in a multiferroic Josephson junction. [PDF]

Nat Commun
Yang HY, Cuozzo JJ, Bokka AJ, Qiu G, Eckberg C, Lyu Y, Huyan S, Chu CW, Watanabe K, Taniguchi T, Wang KL.   +10 more
europepmc   +1 more source