Results 261 to 270 of about 28,041 (324)

Crypt4GH-JS: securely storing sensitive data online with client-side encryption. [PDF]

Bioinformatics
Thelen F, Hochmuth J, Griep S, Schwab B, Goesmann A, Förster F.   +5 more
europepmc   +1 more source

The Super Enhancer‐Driven Long Noncoding RNA PRKCQ‐AS1 Promotes Neuroblastoma Tumorigenesis by Interacting With MSI2 Protein and Is Targetable by Small Molecule Compounds

Advanced Science, EarlyView.
PRKCQ‐AS1 is overexpressed due to transcriptional super‐enhancers. PRKCQ‐AS1 RNA forms a complex with MSI2 protein to induce BMX mRNA stabilization and overexpression, ERK protein phosphorylation and neuroblastoma cell proliferation. Compound NSC617570 blocks PRKCQ‐AS1 binding to MSI2, leading to BMX mRNA disassociation from MSI2 protein, BMX reduction,
Sujanna Mondal, Pei Y. Liu, Janith Seneviratne, Antoine De Weck, Pooja Venkat, Chelsea Mayoh, Jing Wu, Jesper Maag, Jingwei Chen, Matthew Wong, Nenad Bartonicek, Poh Khoo, Lei Jin, Louise E. Ludlow, David S. Ziegler, Toby Trahair, Pieter Mestdagh, Belamy B. Cheung, Jinyan Li, Marcel E. Dinger, Ian Street, Xu D. Zhang, Glenn M. Marshall, Tao Liu   +23 more
wiley   +1 more source

Advancing Allogeneic NK Cell Immunotherapy through Microfluidic Gene Delivery

Advanced Science, EarlyView.
The Y‐Hydroporator is a microfluidic gene delivery platform designed for allogeneic NK cell‐based immunotherapies. It achieves highly efficient gene delivery while preserving high cell viability and functionality. By producing engineered NK cells with enhanced cytotoxicity, the platform addresses critical limitations of autologous cell therapy ...
Hyelee Kim, Mujin Lee, Bohwa Han, Jinho Kim, Duck Cho, Junsang Doh, Aram J. Chung   +6 more
wiley   +1 more source

FREQ‐NESS Reveals the Dynamic Reconfiguration of Frequency‐Resolved Brain Networks During Auditory Stimulation

Advanced Science, EarlyView.
A new analytical pipeline, FREQuency‐resolved Network Estimation via Source Separation (FREQ‐NESS), reveals how the brain at rest is organized in frequency‐specific networks and dynamically rearranges during auditory stimulation. By analyzing source‐reconstructed magnetoencephalography (MEG) data, FREQ‐NESS uncovers the networks' prominence, spatial ...
Mattia Rosso, Gemma Fernández‐Rubio, Peter Erik Keller, Elvira Brattico, Peter Vuust, Morten L Kringelbach, Leonardo Bonetti   +6 more
wiley   +1 more source

High‐Speed 3D Printing Coupled with Machine Learning to Accelerate Alloy Development for Additive Manufacturing

Advanced Science, EarlyView.
This work shows combining high‐throughput experiments of metal 3D printing with data science‐driven prediction leads to faster alloy development. Researchers develop steel alloy specimens specifically for 3D printing by adjusting aluminum content (0–10 wt.%) and energy input during printing.
Avinash Hariharan, Marc Ackermann, Stephan Koss, Ali Khosravani, Johannes Henrich Schleifenbaum, Patrick Köhnen, Surya R. Kalidindi, Christian Haase   +7 more
wiley   +1 more source

Reprogramming the Tumor Immune Microenvironment with ICAM‐1‐Targeted Antibody‒Drug Conjugates and B7‐H3‐CD3 Bispecific Antibodies

Advanced Science, EarlyView.
Reprogramming the tumor immune microenvironment is crucial for transforming immune “cold” tumors into “hot” inflammatory tumors. The investigation reveals that the combination of ICAM‐1‐Dxd with B7‐H3‐CD3 bispecific antibodies not only demonstrates significant inhibitory effects on tumor growth and metastasis but also plays a vital role in ...
Shoubing Zhou, Mengyu Hong, Dan Zhao, Wenyu Li, Xiaolong Yuan, Yinghong Wang, Hualong Li, Yang Yang, Tengchuan Jin, Jing Pan   +9 more
wiley   +1 more source

A combinatory approach of non-chain ring and henon map for image encryption application. [PDF]

Sci Rep
Mohi Ud Din S, Shah T, Alblehai F, Nooh S, Jamal SS.   +4 more
europepmc   +1 more source

Nanoscale Resist‐Free Patterning of Halogenated Zeolitic Imidazolate Frameworks by Extreme UV Lithography

Advanced Science, EarlyView.
This work presents a direct, resist‐free patterning method for metal–organic frameworks using extreme ultraviolet (EUV) lithography, achieving a resolution of 40 nm. The EUV mechanism is investigated through synchrotron in situ X‐ray photoelectron spectroscopy.
Weina Li, Tianlei Ma, Pengyi Tang, Yunhong Luo, Hui Zhang, Jun Zhao, Rob Ameloot, Min Tu   +7 more
wiley   +1 more source

A novel multiple-image encryption with multi-petals structured light. [PDF]

Sci Rep
Tian H, Zhuang X, Yan A, Zhang H.
europepmc   +1 more source