Results 41 to 50 of about 1,890,742 (270)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

Beyond Digital Literacy: Building Youth Digital Resilience Through Existing “Information Sensibility” Practices

open access: yesSocial Sciences
Youth media consumption and disordered eating practices have historically been subjects of moral panics, often resulting in protective, deficit-based interventions like content removal. We argue for interventions which instead equip youth to evaluate and
Amelia Hassoun   +9 more
doaj   +1 more source

Examining trade-offs between social, psychological, and energy potential of urban form [PDF]

open access: yes, 2019
Urban planners are often challenged with the task of developing design solutions which must meet multiple, and often contradictory, criteria. In this paper, we investigated the trade-offs between social, psychological, and energy potential of the ...
Bielik, Martin   +7 more
core   +3 more sources

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait   +23 more
wiley   +1 more source

Integrating street view imagery and taxi trajectory for identifying urban function of street space

open access: yesGeo-spatial Information Science
Street space is a crucial component of public space, serving as a site for a variety of human activities. However, prior studies have primarily focused on the traffic function of street space, neglecting other functional types, such as residential and ...
Mianxin Gao   +6 more
doaj   +1 more source

On the Perturbation of Self-Organized Urban Street Networks

open access: yes, 2019
We investigate urban street networks as a whole within the frameworks of information physics and statistical physics. Urban street networks are envisaged as evolving social systems subject to a Boltzmann-mesoscopic entropy conservation.
Benoit, Jerome, Jabari, Saif Eddin
core   +1 more source

Enhancing Energy Minimization Framework for Scene Text Recognition with Top-Down Cues [PDF]

open access: yes, 2016
Recognizing scene text is a challenging problem, even more so than the recognition of scanned documents. This problem has gained significant attention from the computer vision community in recent years, and several methods based on energy minimization ...
Alahari, Karteek   +2 more
core   +4 more sources

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach   +23 more
wiley   +1 more source

Street View Imagery Analysis in a Computational Notebook

open access: yesREGION
Street view imagery, capturing detailed streetscapes at human eye-level, has received significant attention in the past decade. Street view images can be leveraged to observe the built environment from both element- and scene-levels.
Yuhao Kang
doaj   +1 more source

View from the Street: Partnerships and Collaboration [PDF]

open access: yes, 2016
Richard Simonds and Josh Reynolds are social workers in Houston. Richard is the Director of THRIVE Connection at Family Houston. Josh is the Director of United Way Care for Elders, an initiative of United Way of Greater Houston that is a collaborative of
Reynolds, Josh, Simonds, Richard
core   +1 more source

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