Results 141 to 150 of about 5,501,103 (350)

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Consideration of Spatially Infinite Loads in the Problem for a Layer with a Cylindrical Cavity and Continuous Supports

Computation
An analytical method is proposed for determining the stress-strain state in an elastic layer with a cylindrical cavity supported by linear continuous supports perpendicular to the cavity.
Nataliia Ukrayinets, Tetyana Alyoshechkina, Vitaly Miroshnikov, Oleksandr Savin, Basheer Younis, Vitalii Vynohradov, Olena Murahovska   +6 more
doaj   +1 more source

Shear Strength and Dsc Analysis of High-Temperature Solders [PDF]

, 2013
Roman Koleňák, Maroš Martinkovič, Monika Koleňáková   +2 more
openalex   +1 more source

Tensile strength analysis of automatic periodic stimulation for continuous intraoperative neural monitoring in a piglet model. [PDF]

Sci Rep, 2021
Wang T, Dionigi G, Zhao Y, Zhang D, Pino A, Dralle H, Wu CW, Zhou L, Sun H.   +8 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Design Improvement of Mechanical Transmission for Tracked Small Agricultural Transporters through Gear Strength Analysis [PDF]

, 2016
Hong-Gon Kim, Yeon-Ju Jo, Chul-Soo Kim, Yong-Ho Han, Dae–Cheol Kim   +4 more
openalex   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Strength Analysis and Design of a Multi-Bridge V-Shaped Rotor for High-Speed Interior Permanent Magnet Synchronous Motors

Actuators
High-speed operation is a crucial approach for achieving high power density of drive motors for new energy vehicles. However, mechanical strength of the rotor has become the primary bottleneck in the development of high-speed drive motors.
Kun Zhou, Dongxiong Wang, Zewen Yu, Xianju Yuan, Ming Zhang, Yu Zheng   +5 more
doaj   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Design and Strength Safety Analysis of Pressure Relief Device for Perforating Gun

Shiyou jixie
Perforation detonation produces high-temperature and high-pressure gas. If the pressure exceeds the internal pressure strength of the gun body， the perforating gun would break， leading to accidents such as gun expansion and jamming.
Li Mingfei, Zhang Danpeng, Li Bihong, He Jianlei, Tian Bin, Lin Liming, Dou Yihua   +6 more
doaj   +1 more source