Results 31 to 40 of about 27,040,201 (217)
Hierarchical fiber bundle strength statistics [PDF]
, 2012 Multi-scale modeling is currently one of the most active research topics in a wide range of disciplines. In this thesis we develop innovative hierarchical multi-scale models to analyze the probabilistic strength of fiber bundle structures.
Alsaeed Mahmoud Abdalrahman, Tamer
core +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
, 2018 Párraga-Montilla, JA, García-Ramos, A, Castaño-Zambudio, A, Capelo-Ramírez, F, González-Hernández, JM, Cordero-Rodríguez, Y, and Jiménez-Reyes, P. Acute and delayed effects of a resistance training session leading to muscular failure on mechanical ...
Capelo Ramírez, Fernando +6 more
core +1 more source
Individual differences in the perception of similarity and difference [PDF]
, 2008 Thematically related concepts like coffee and milk are judged to be more similar than thematically unrelated concepts like coffee and lemonade. We investigated whether thematic relations exert a small effect that occurs consistently across participants ...
Simmons, S +4 more
core +1 more source
, 2021 The aim of this present study was to compare the reactive strength index (RSI) characteristics and trial to trial reliability of U17, U19 and Senior female international soccer players. Fifty – seven elite female soccer player participated in the study, (
Doyle, Brian, Horan, Dan, Browne, Declan
core +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
, 2022 This study aimed to compare the acute effect of traditional (TR), cluster (CL), and rest redistribution (RR) set configurations on neuromuscular and perceptual measures of fatigue.
Dr. Cuevas-Aburto, Jesualdo +7 more
core +1 more source