Results 21 to 30 of about 49,616 (265)

A Modular Vaccine Platform Against SARS‐CoV‐2 Based on Self‐Assembled Protein Nanoparticles

Advanced Science, EarlyView.
A modular BP26 nanoparticle vaccine platform incorporating the SpyTag/SpyCatcher system enables high‐density, repetitive antigen display with post‐expression flexibility. Conjugation of the SARS‐CoV‐2 RBD to BP26 nanoparticles elicits strong humoral immunity and confers protection against viral challenge in vivo.
Seojung Lee, Yejin Jang, Yujin Kim, Yumi Shin, Ji‐Joon Song, Meehyein Kim, Sangyong Jon   +6 more
wiley   +1 more source

Frequent Antenatal Care Visits Increase Institutional Delivery at Dabat Health and Demographic Surveillance System Site, Northwest Ethiopia

Journal of Pregnancy, 2019
Background Early diagnosis of pregnancy, professional follow-up, and skilled delivery service are the main interventions that reduce maternal morbidity and mortality.
Abel Fekadu, Mezgebu Yitayal, G. Alemayehu, S. Abebe, T. Ayele, Amare Tariku, Gashaw Andargie, D. Teshome, K. Gelaye   +8 more
semanticscholar   +1 more source

Sequential Simulation (SqS): an empirical and theoretical model [PDF]

, 2018
Ethics statement: The authors declare that they have followed the guidelines for scientific integrity and professional ethics. The article does not contain any studies with human or animal subjects.
McMeekin, Peter, Platt, Alan, Prescott-Clements, Linda   +2 more
core   +2 more sources

Autophagy Activators Normalize Aberrant Tau Proteostasis and Rescue Synapses in Human Familial Alzheimer's Disease iPSC‐Derived Cortical Organoids

Advanced Science, EarlyView.
A new cerebrocortical organoid model using isogenic hiPSCs with familial Alzheimer's mutations recapitulates key AD features, including amyloid‐beta and phospho‐Tau aggregation, neuronal hyperexcitability, and synapse loss. Single‐cell RNA‐seq reveals aberrant pathways in excitatory and inhibitory neurons.
Sergio R. Labra, Jadon Compher, Akhil Prabhavalkar, Mireya Almaraz, Claudia Cedeño Kwong, Christine Baal, Maria Talantova, Nima Dolatabadi, Julian Piña‐Sanz, Yubo Wang, Leonard Yoon, Swagata Ghatak, Zi Gao, Yuting Zhang, Dorit Trudler, Lynee Massey, Wei Lin, Anthony Balistreri, Michael Bula, Nicholas J. Schork, Tony S. Mondala, Steven R. Head, Jeffery W. Kelly, Stuart A. Lipton   +23 more
wiley   +1 more source

Examining the Role of the Catholic Environment in Students’ Search for Meaning [PDF]

, 2016
Emerging research illustrates that undergraduate students are searching for meaning in their lives, yet postsecondary institutions generally do little to support them in exploring such issues (Astin et al., 2005b).
Dean, Kathleen Lis, Dooley, Jonathan C., Jessup-Anger, Jody, Leih, Rachel, Mueller, Elizabeth   +4 more
core   +1 more source

Process evaluation of appreciative inquiry to translate pain management evidence into pediatric nursing practice [PDF]

, 2010
Background Appreciative inquiry (AI) is an innovative knowledge translation (KT) intervention that is compatible with the Promoting Action on Research in Health Services (PARiHS) framework. This study explored the innovative use of AI as a theoretically
A Challis, A Franke, A Kitson, A Kitson, A Twycross, Bonnie Stevens, C Carter, C Van Hulle Vincent, CA Estabrooks, DA Jones, DL Cooperrider, DS Thompson, DS Thompson, GR Bushe, GR Bushe, I Ellis, Improved Clinical Effectiveness through Behavioural Research Group (ICEBeRG), J Corbin, J Ploeg, J Reed, J Ritchie, J Rycroft-Malone, J Rycroft-Malone, JM Grimshaw, Judy Watt-Watson, JW Creswell, Kate Seers, L McCleary, M Collins, M Eccles, M Hulscher, M Latimer, M Sandelowski, MA Dufault, N Feeley, ND Sharp, P Craig, RC Moody, S Scott-Findlay, S Spenceley, S Tracy, Souraya Sidani, T Kavanagh, T Kavanagh, Tricia Kavanagh, WA Firestone   +45 more
core   +4 more sources

Multimodal Wearable Biosensing Meets Multidomain AI: A Pathway to Decentralized Healthcare

Advanced Science, EarlyView.
Multimodal biosensing meets multidomain AI. Wearable biosensors capture complementary biochemical and physiological signals, while cross‐device, population‐aware learning aligns noisy, heterogeneous streams. This Review distills key sensing modalities, fusion and calibration strategies, and privacy‐preserving deployment pathways that transform ...
Chenshu Liu, Haolin Fan, Minwoo Kim, Tong Zhou, Pinyi Yang, Lingdi Zhao, Yiran Wang, Ziyuan Che, Chia‐Wei Liu, Bingbing Li, Yangzhi Zhu   +10 more
wiley   +1 more source

Deep Learning‐Assisted Coherent Raman Scattering Microscopy

Advanced Intelligent Discovery, EarlyView.
The analytical capabilities of coherent Raman scattering microscopy are augmented through deep learning integration. This synergistic paradigm improves fundamental performance via denoising, deconvolution, and hyperspectral unmixing. Concurrently, it enhances downstream image analysis including subcellular localization, virtual staining, and clinical ...
Jianlin Liu, Rujia Liu, Xinyan Zhang, Xun Chen, Shuhua Yue   +4 more
wiley   +1 more source

Too Many Teens: Preventing Unnecessary Out-Of-Home Placements [PDF]

, 2015
The child welfare system was created to care for abused and neglected children. But too often, teenagers are landing in the system because they simply aren't getting along with their parents.
Anne Holton, Roque Gerald, Tamara Horne
core  

Roadmap on Artificial Intelligence‐Augmented Additive Manufacturing

Advanced Intelligent Systems, EarlyView.
This Roadmap outlines the transformative role of artificial intelligence‐augmented additive manufacturing, highlighting advances in design, monitoring, and product development. By integrating tools such as generative design, computer vision, digital twins, and closed‐loop control, it presents pathways toward smart, scalable, and autonomous additive ...
Ali Zolfagharian, Liuchao Jin, Qi Ge, Wei‐Hsin Liao, Andrés Díaz Lantada, Francisco Franco Martínez, Tianyu Zhang, Tao Liu, Charlie C. L. Wang, Mohammad Hossein Mosallanejad, Reza Ghanavati, Abdollah Saboori, Alejandro De Blas De Miguel, William Solórzano‐Requejo, Yi Cai, Xiangyang Dong, Huangyi Qu, Najmeh Samadiani, Guangyan Huang, Austin Downey, Yanzhou Fu, Lang Yuan, Tsz‐Kwan (Glory) Lee, Arbind Agrahari Baniya, Eisha Waseem, Abdul Rahman Sani, Abbas Z. Kouzani, Yijia Wu, Markus P. Nemitz, Masoud Shirzad, Dageon Oh, Seung Yun Nam, Amedeo Franco Bonatti, Irene Chiesa, Gabriele Maria Fortunato, Giovanni Vozzi, Carmelo De Maria, Mahdi Bodaghi   +37 more
wiley   +1 more source