Results 41 to 50 of about 808,099 (278)

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Some Syllabi Descriptions: Strengths and Weaknesses

open access: yesHOW, 2016
When designing a "syllabus" at the beginning of a course or semester, we find some difficulties concerning the appropriate selection of the type of syllabus we want to develop through the course.
Aida Bastidas, Vicente Araujo
doaj  

Business environment in the Czech Republic before and after the Integration into the EU

open access: yesActa Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2006
The paper is a particular contribution to study of changes in the business environment, which were induced by the Integration of the Czech Republic to the European Union.
Renata Kučerová, Zdeněk Pošvář
doaj   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

open access: yesFEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan   +6 more
wiley   +1 more source

Finnish vocational education and training in comparison: Strengths and weaknesses

open access: yesInternational Journal for Research in Vocational Education and Training, 2014
The study investigates how the Finnish model of providing initial vocational education and training (IVET) has succeeded in terms of enhancing educational progress and employability.
Maarit Virolainen   +1 more
doaj   +1 more source

A service-learning program assessment: Strengths, weaknesses and impacts on students

open access: yesIntangible Capital, 2023
Purpose: This paper aims to research the strengths and weaknesses of service-learning programs in order to identify the challenges of their application, the educational possibilities of service-learning and the impact on students.
Rocío Samino García
doaj   +1 more source

BOOK REVIEW OF THE HAPPINESS PROJECT WRITTEN BY GRETCHEN RUBIN [PDF]

open access: yes, 2016
This book review analyzes the strengths and weaknesses of Gretchen Rubin’s The Happiness Project. The Happiness Project is a novel about how to pursuit happiness in life.
Prasetyo, Mochammad Afrizal
core   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

THE RESPONSIBILITIES, STRENGTHS, AND WEAKNESSES OF KITCHEN SECTION AT SAHID JAYA HOTEL SOLO [PDF]

open access: yes, 2010
Hotel has an important role in supporting the development of the tourism industry. Many ways are done to attract the guest to use service and facilities in a hotel. One of the efforts is maintaining Food and Beverage well to attract the guests.
Wicaksono, Danar Rizki
core  

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