Results 61 to 70 of about 808,099 (278)

Impact of APOE ε4 Genotype Load on Cognitive Function and Lipid Metabolism in Patients With Cerebral Small Vessel Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Apolipoprotein ε4 (APOE ε4) is a potent genetic risk factor for Alzheimer's disease (AD). However, its role in cerebral small vessel disease (CSVD) remains unclear. Given the clinical and pathological similarities between CSVD and AD, this study aimed to investigate the associations of APOE ε4 gene dosage with cognitive function and
Tingru Jin   +6 more
wiley   +1 more source

Stronger Partnerships for Safer Food: An Agenda for Strengthening State and Local Roles in the Nation's Food Safety System [PDF]

open access: yes, 2009
Examines federal, state, and local agencies' responsibilities, strengths, and weaknesses in ensuring food safety. Recommends systemwide reforms to enhance state and local roles and improve surveillance, outbreak response, and regulation and ...
Michael R. Taylor, Stephanie D. David
core  

Higher Amyloid and Tau Burden Is Associated With Faster Decline on a Digital Cognitive Test

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective A 2‐min digital clock‐drawing test (DCTclock) captures more granular features of the clock‐drawing process than the pencil‐and‐paper clock‐drawing test, revealing more subtle deficits at the preclinical stage of Alzheimer's disease (AD). A previous cross‐sectional study demonstrated that worse DCTclock performance was associated with
Jessie Fanglu Fu   +16 more
wiley   +1 more source

Reinspection of curriculum areas 1996-97: report from the Inspectorate [PDF]

open access: yes, 1997
FEFC INSPECTION REPORT 109/97 REINSPECTION OF CURRICULUM AREAS, OCTOBER 1996 TO MAY 1997 The Council has agreed that colleges with curriculum areas judged by the inspectorate to have more weaknesses than strengths (grades 4 or 5) may have their ...

core  

Network Localization of Fatigue in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo   +12 more
wiley   +1 more source

ASPECTOS DETERMINANTES EN LA INTERNACIONALIZACIÓN DE LA EMPRESA FAMILIAR

open access: yesRevista de Estudios Empresariales. Segunda Época, 2007
Internationalization strategy is an important decision for both family and non family firms.Some singularities of family firms, pointed out by literature as strengths and weaknesses, can have influence on the success or failure of their international ...
Rubén Fernández Ortiz   +2 more
doaj  

BOOK REVIEW OF THE GUARDIAN WRITTEN BY NICHOLAS SPARKS [PDF]

open access: yes, 2015
Book review of The Guardian by Nicholas Sparks is to understand the strengths and weaknesses of The Guardian novel. This analysis uses intrinsic aspects which are theme, character, and setting as analysis focus. The Guardian tells about a journey to find
Sutopo , Galuh Agliesta Erawati
core  

Frailty Exacerbates Disability in Progressive Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background To evaluate frailty in severe progressive multiple sclerosis (PMS) and to investigate the underlying mechanisms. Methods This prospective, cross‐sectional, multicenter study enrolled a late severe PMS group requiring skilled nursing (n = 53) and an age, sex, and disease duration‐matched control PMS group (n = 53).
Taylor R. Wicks   +10 more
wiley   +1 more source

Looking Inside the Strategic Plans: Strengths and Weaknesses of Turkish Higher Education Institutions

open access: yesQualitative Research in Education, 2020
As strengths and weaknesses are regarded as internal features of an organization, the present study focused on strengths and weaknesses of Turkish public universities by analyzing the SWOTs (Strengths, Weaknesses, Opportunities, Threats) of twenty ...
Abdullah Selvitopu, Metin Kaya
doaj   +1 more source

Towards a hybrid testing process unifying exploratory testing and scripted testing [PDF]

open access: yes, 2014
CONTEXT Given the current state of the art in research, practitioners are faced with the challenge of choosing scripted testing (ST) or exploratory testing (ET). OBJECTIVE This study aims at systematically incorporating strengths of ET and ST in a hybrid
Ahonen   +21 more
core   +1 more source

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