Results 81 to 90 of about 938,342 (303)
High burden of impetigo and scabies in a tropical country. [PDF]
BACKGROUND: Impetigo and scabies are endemic diseases in many tropical countries; however the epidemiology of these diseases is poorly understood in many areas, particularly in the Pacific.
Steer Andrew C. +31 more
core +2 more sources
Artificial Intelligence‐Guided Phenotypic Drug Repurposing Against Streptococcus pneumoniae
Integrated artificial intelligence (AI) ensembles identify highly potent repurposed drugs against Streptococcus pneumoniae. Prospective virtual screening of 6747 drugs uncovers nine active candidates, including thiostrepton. This drug exhibits low picomolar potency and bypasses established resistance in multidrug‐resistant strains, demonstrating an ...
Joshua S. Fitch +6 more
wiley +1 more source
Lancefield group C streptococci are known to be pathogenic in a number of animal species, but cause human disease much less commonly than do streptococci of scrogroups A or B. Reported cases of bacteremic infection, pneumonia or meningitis in humans have
Allen R Huang, Dalius J Briedis
doaj +1 more source
Post-Streptococcal Uveitis: a Rare Entity
Without appropriate treatment, Group A streptococcal infections can lead to post-streptococcal syndrome, including post-streptococcal uveitis. This should be kept in mind in young patients with acute bilateral non-granulomatous anterior uveitis, in order
Hofer, M. +17 more
core +1 more source
Streptococcal mannose phosphotransferase system component IID (Man‐PTSIID) is identified as a novel RANK‐binding osteoclastogenic factor. By directly binding to RANK and activating NF‐κB independently of TLR2, Man‐PTSIID drives osteoclastogenesis and inflammatory bone destruction, uncovering an unexpected microbial mechanism underlying streptococcal ...
Chaeyeon Park +13 more
wiley +1 more source
In hospital infection-related mortality in patients with invasive group B streptococcal infections according to various characteristics.
Louis Valiquette (186543) +5 more
core +1 more source
Targeting the YAP‐BST2 Axis Overcomes Intrinsic Anti‐PD‐1 Resistance in Metastatic Gastric Cancer
Concurrent YAP hyperactivation and Tp53 loss in Atp4b‐expressed parietal cell lineage drives gastric cancer initiation, multi‐organ metastasis, and intrinsic resistance to anti‐PD‐1 therapy. BST2 emerges as a direct YAP‐TEAD transcriptional target that engages PIRA2 on myeloid cells to establish an immunosuppressive microenvironment.
Weihong Zhang +17 more
wiley +1 more source
Pediatric autoimmune neuropsychiatric disorders related to streptococcal infections, or more commonly known as PANDAS, are a hypothesized disorder characterized by the sudden onset of obsessive–compulsive symptoms and/or tic disorders following Group A ...
Twisha Ghosh Dastidar
doaj +1 more source
Cardiac and non-cardiac manifestations of infection caused by group A β-hemolytic Streptococcus [PDF]
G.V. Santalova, P.A. Lebedev, A.A. Garanin, A.V. Lyamin, M.E. Kuzin Samara State Medical University, Samara, Russian Federation Infection caused by group A β-hemolytic Streptococcus (GABHS) is characterized by significant diversity of clinical ...
P.A. Lebedev +3 more
doaj
Bioactive phenylboronic acid–chitosan nanoparticles enable responsive silymarin delivery for post‐hepatectomy liver protection. The nanoplatform integrates antioxidant and antibacterial functions, improves hepatic recovery, and is associated with coordinated shifts in gut microbiota, metabolites, cytokines, and hepatic proteomic pathways, suggesting a ...
Jinjin Tong +9 more
wiley +1 more source

