Results 41 to 50 of about 28,352 (195)

Histidine Supplementation Stabilizes Hearing and Vision and Improves Growth in HARS1‐Related Autosomal Recessive Disorder Associated With Usher‐Like Symptoms

American Journal of Medical Genetics Part A, Volume 200, Issue 10, Page 2289-2308, October 2026.
ABSTRACT Autosomal recessive HARS1‐related disorder (originally described as Usher syndrome type 3B) caused by a homozygous Y454S variant in the histidyl‐tRNA synthetase gene (HARS1) is characterized by progressive sensorineural hearing and vision loss and respiratory deterioration with risk for sudden death following febrile illnesses.
Victoria Mok Siu, Rosan Kenana, Rana Chakrabarti, Sarah D. P. Wilhelm, Joseph Andrews, Susan J. Leat, Christina Parker, Michael Miller, Leslie A. Nangle, Wendy McCaul, Ashfia Chowdhury, Natalie Hutchings, Ryan A. Adams, Lauren Guy, Mandy Rhody, Verena Juncal, Marisa I. Mendes, Desiree E. C. Smith, Gajja S. Salomons, Angelica A. Moresco, Daphne L. McCulloch, D. Holmes Morton, Ilka U. Heinemann, C. Anthony Rupar   +23 more
wiley   +1 more source

Different antibiotic treatments for group A streptococcal pharyngitis (Review)

, 2021
BACKGROUND: Antibiotics provide only modest benefit in treating sore throat, although their effectiveness increases in people with positive throat swabs for group A beta-haemolytic streptococci (GABHS).
Christiaens, Thierry, De Sutter, An Im, van Driel, Mieke L, Thorning, Sarah   +3 more
core   +1 more source

Sustained Therapeutic Efficacy of Intravenous Plasminogen Concentrate in Pediatric Patients With Type 1 Plasminogen Deficiency: An Analysis of Dosing Parameters and Clinical Outcomes

Pediatric Blood &Cancer, Volume 73, Issue 9, September 2026.
ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar, Karen Thibaudeau, Mary Mathias, Heather McDaniel, Madlen Reschke, Klaus Tenbrock, Joseph M. Parker, Amy Shapiro   +7 more
wiley   +1 more source

Does a simple educational exercise influence practice in acute tonsillitis in children? [PDF]

, 2013
Aim: To assess the concordance of treatment of children attending with tonsillitis in Paediatric Accident and Emergency with established guidelines, and subsequent review of the management of this condition after a simple educational exercise. Methods:
Attard Montalto, Simon, Mulvaney, Shirley   +1 more
core  

Clinical predictors of childhood streptococcal pharyngitis

, 2008
Background Antibiotic prescription for the management of all acutepharyngitis seems to be increasing recently. Streptococcal pharyngitisis the one that has strong indication for antibiotic prescription.
Rizanda Machmud, Rulifa Syahroel, Amrin Alkamar, A. Aziz Djamal   +3 more
core   +1 more source

The molecular characterisation of Group A Streptococcus among children with phyryngitis in the Vanguard community (Bonteheuwel [PDF]

, 2012
Includes abstract.
Muhamed, Babu
core   +1 more source

Vasopressor‐Associated Limb Ischemia Resulting in Quadruple Amputation in Suspected Septic Shock

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Vasopressor‐associated limb ischemia (VALI) is a rare but devastating complication of vasopressor therapy in septic shock. This case shows catastrophic four‐limb amputation in a 26‐year‐old obese male with suspected septic shock. This case illustrates the complex interplay between prolonged high‐dose vasopressor therapy, morbid obesity, and ...
Muni Rubens, Venkataraghavan Ramamoorthy, Krimal Shah, Ashley Rodriguez, Brian Murillo, Karelis Lopez Muniz, Anshul Saxena, Peter McGranaghan, Tina Sanjar   +8 more
wiley   +1 more source

DIAGNOSIS OF ACUTE PHARYNGITIS IN CHILDREN

Педиатрическая фармакология, 2014
This literature review is dedicated to the issue of clinical and laboratory diagnosis of acute pharyngitis in children and adolescents. Relevance of the topic is justified by omnipresent (up to 70% of patients with acute pharyngitis) unreasonable ...
T. V. Kulichenko, A. M. Kabaloeva, Yu. S. Lashkova, M. A. Lazareva   +3 more
doaj   +1 more source

Prevalence of group A β-hemolytic streptococcal throat carriage and prospective pilot surveillance of streptococcal sore throat in Ugandan school children

International Journal of Infectious Diseases, 2020
Objectives: Group A β-hemolytic Streptococcus (GAS), also known as Streptococcus pyogenes, is responsible for an annual 600 million cases of acute pharyngitis globally, with 92% of those infections occurring in low-resource settings. Further knowledge of
Alyssa DeWyer, Amy Scheel, Allison R. Webel, Chris T. Longenecker, Jennipher Kamarembo, Twalib Aliku, Mark E. Engel, Asha C. Bowen, Freddie Bwanga, Ian Hovis, Aileen Chang, Rachel Sarnacki, Craig Sable, James B. Dale, Jonathan Carapetis, Joselyn Rwebembera, Emmy Okello, Andrea Beaton   +17 more
doaj   +1 more source

Acute Rheumatic Fever Without Pharyngitis: A Case Report

Journal of General and Family Medicine, Volume 27, Issue 5, September 2026.
ABSTRACT An 18‐year‐old man presented with fatigue and polyarthralgia refractory to nonsteroidal anti‐inflammatory drugs (NSAIDs). He had no history of sore throat or other upper respiratory symptoms. Reactive arthritis was initially suspected. However, persistent symptoms, fever, polyarthritis, a cardiac murmur, atrioventricular block, and an elevated
Hiroki Suzuyama, Ryutaro Hashimoto, Fumiya Taketomi, Ikuma Noge, Tadaaki Arimura, Hiroaki Takeoka, Atsuhiko Sakamoto, Shigeki Nabeshima   +7 more
wiley   +1 more source