Results 191 to 200 of about 417,094 (305)

Proteomic and Metabolomic Analyses Provide Insights into the Mechanism on Arginine Metabolism Regulated by tRNA Modification Enzymes GidA and MnmE of Streptococcus suis

, 2020
Ting Gao, Fangyan Yuan, Zewen Liu, Wei Liu, Danna Zhou, Keli Yang, Rui Guo, Wan Liang, Geng Zou, Rui Zhou, Yongxiang Tian   +10 more
openalex   +1 more source

Population pharmacokinetics of levofloxacin in breastmilk in patients with rifampicin‐resistant tuberculosis

British Journal of Clinical Pharmacology, EarlyView.
Levofloxacin is a widely used antibiotic included in rifampicin‐resistant tuberculosis (RR‐TB) treatment. Data describing levofloxacin concentrations in breastmilk and infant exposure are limited. We analysed data from two South African studies of breastfeeding women receiving levofloxacin (750–1000 mg daily) for RR‐TB.
Sharon Sawe, Lufina Tsirizani, Buyisile Mkhize, Lubbe Wiesner, Gary Maartens, Francesca Conradie, Richard Court, Marian Loveday, Catriona Waitt, Paolo Denti   +9 more
wiley   +1 more source

An analysis of the vaginal microbiota in women positive for group B Streptococcus during the third trimester of pregnancy [PDF]

Tong Zhang, Chong-xin Tong, Jialin Wang, Shuang Gao, Kui Li, Xiaona Wang   +5 more
openalex   +1 more source

Population pharmacokinetic modelling of amoxicillin in human breast milk—A contribution from the ConcePTION project

British Journal of Clinical Pharmacology, EarlyView.
Aims Amoxicillin, a widely used β‐lactam antibiotic, requires improved pharmacokinetic characterization during breastfeeding. This study used a population pharmacokinetic (PopPK) approach to model amoxicillin concentrations in breast milk, identify variability sources and estimate infant exposure, applying worst‐case scenarios.
Sarah Baklouti, Virginie Rigourd, Alice Panchaud, Hedvig Nordeng, Karel Allegaert, Pieter Annaert, Miao‐Chan Huang, Anaelle Monfort, Monia Guidi, Peggy Gandia   +9 more
wiley   +1 more source

Liver abscess and bacteremia caused by <i>Streptococcus constellatus</i> with suspected ileocecal valve lesion as the entry point. [PDF]

IDCases
Takeda Y, Kobayashi T, Van Sickels N, Yoshida A.   +3 more
europepmc   +1 more source

Quantitative Analysis Reveals Hitchhiking Drives Polysorbate Hydrolase Persistence Via Host Cell Protein–Antibody Interactions

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Polysorbate‐degrading host cell proteins (HCPs) represent a critical challenge in the manufacturing of monoclonal antibody therapeutics due to their potential to persist during downstream processing. While their enzymatic activity has been characterized, the role of direct HCP‐mAb interactions, particularly those involving polysorbate ...
Melanie Maier, Lukas Griesinger, Matthias Franzreb, Simon Kluters   +3 more
wiley   +1 more source

From pathogen to prognosis: microbial keratitis spectrum and treatment outcomes in a 5-Year tertiary center experience. [PDF]

J Ophthalmic Inflamm Infect
Ince BAC, Ayyildiz O, Ozge G.
europepmc   +1 more source

Ten Years of Surveillance for Invasive Streptococcus pneumoniae during the Era of Antiretroviral Scale-Up and Cotrimoxazole Prophylaxis in Malawi

, 2011
Dean Everett, Mavuto Mukaka, Brigitte Denis, Stephen B. Gordon, Enitan D. Carrol, Joep J. van Oosterhout, Elizabeth Molyneux, Malcolm E. Molyneux, Neil French, Robert S. Heyderman   +9 more
openalex   +2 more sources

Functional CRISPR‐Cas9 knockout screening of the genetic determinants of human fibroblast migration propensity

Biotechnology Progress, EarlyView.
Abstract Directional cell migration plays a central role in a wide range of physiological and pathological conditions, such as embryonic development or tumor metastasis. Steps involved in cell migration include cell polarization, formation of membrane protrusions at the cell front side and adhesion disassembly at the rear side, and a general ...
Antonio Mazzei, Sebastian Martewicz, Ramin Amiri, Meihua Cui, Nicola Elvassore, Camilla Luni   +5 more
wiley   +1 more source

ResMicroDb: a comprehensive database and analysis platform for the human respiratory microbiome. [PDF]

Nucleic Acids Res
Ji X, Qian Q, Zhang H, Cai Q, Zhang K, Xiao J, Jiang X, Li M.   +7 more
europepmc   +1 more source