Results 81 to 90 of about 20,940 (258)

Associations of Nucleoside Diphosphate‐Linked Moiety X‐Type Motif 15 Variants With Neutropenia During Antiviral Therapy for Cytomegalovirus Disease in Pediatric Liver Transplant Recipients

Transplant Infectious Disease, EarlyView.
NUDT15 variants were associated with an increased risk of neutropenia in pediatric liver transplant recipients receiving GCV/VGCV treatment. Genetic screening before treatment initiation may help optimize antiviral therapy, minimize hematological toxicity, and improve patient management.
Ken‐ichi Iwata, Yuka Torii, Yuto Fukuda, Kazunori Haruta, Makoto Yamaguchi, Takako Suzuki, Yasuhiro Ogura, Jun‐ichi Kawada   +7 more
wiley   +1 more source

Fluoridated elastomers: Effect on the microbiology of plaque [PDF]

, 2004
The objective of this study was to investigate the effect of fluoridated elastomeric ligatures on the microbiology of local dental plaque in vivo. This randomized, prospective, longitudinal, clinical trial had a split-mouth crossover design. The subjects
Alstad, Banks, C.W.Ian Douglas, Corbett, Forsberg, Hallgren, Hallgren, Huser, Maltz, Mattick, Michael V. Martin, Philip E. Benson, Sakamaki, Scheie, Svanberg, ten Cate, Wilson, Wiltshire, Wiltshire   +18 more
core   +1 more source

Competence in Streptococcus pneumoniae and Close Commensal Relatives: Mechanisms and Implications

Frontiers in Cellular and Infection Microbiology, 2019
The mitis group of streptococci comprises species that are common colonizers of the naso-oral-pharyngeal tract of humans. Streptococcus pneumoniae and Streptococcus mitis are close relatives and share ~60–80% of orthologous genes, but still present ...
Gabriela Salvadori, Roger Junges, Donald A. Morrison, Fernanda C. Petersen   +3 more
doaj   +1 more source

Pantoea agglomerans in Equine Ulcerative Keratitis: Prevalence and Comparative Efficacy of Four Topical Antiseptics

Veterinary Ophthalmology, EarlyView.
ABSTRACT Objective To determine the minimal bactericidal concentration (MBC) and effective contact time of four topical antiseptics—polyhexanide, povidone‐iodine (PVP‐I), hypochlorous acid (HOCl), and N‐acetylcysteine (NAC)—against Pantoea agglomerans, a pathogen frequently isolated in equine ulcerative keratitis.
Frederik Heun, Jessica Meißner, Ann‐Kathrin Schieder, Bernhard Ohnesorge, Claudia Busse   +4 more
wiley   +1 more source

Characterization of bacteriophage communities and CRISPR profiles from dental plaque. [PDF]

, 2014
BackgroundDental plaque is home to a diverse and complex community of bacteria, but has generally been believed to be inhabited by relatively few viruses.
Abeles, Shira R, Boehm, Tobias K, Naidu, Mayuri, Pride, David T, Robles-Sikisaka, Refugio   +4 more
core   +2 more sources

Bezlotoxumab as Treatment for Recurrent/Chronic Clostridioides difficile Infection in Pediatric Stem Cell Transplant Recipients: A Multi‐Institutional Experience

Pediatric Blood &Cancer, Volume 72, Issue 10, October 2025.
ABSTRACT Clostridioides difficile infection (CDI) represents a significant health risk to pediatric stem cell transplant (SCT) patients. In these patients, recurrent CDI is common, requiring prolonged antibiotic usage and increased hospitalization. Bezlotoxumab, a monoclonal antibody that targets the toxin responsible for CDI, has demonstrated efficacy
Aaron E. Fan, Shaikha Alqahtani, Natalie Dailey Garnes, Priti Tewari, Demetrios Petropoulos, Sajad Khazal, Kris Mahadeo, Paige DePriest, Irtiza N. Sheikh   +8 more
wiley   +1 more source

Polymicrobial oral biofilm models: simplifying the complex [PDF]

, 2019
Over the past century, numerous studies have used oral biofilm models to investigate growth kinetics, biofilm formation, structure and composition, antimicrobial susceptibility and host–pathogen interactions.
Appelbaum, Black, Bradshaw, Bryn Short, Ceri, Christopher Delaney, Darveau, Fitzgerald, Gibbons, Gordon Ramage, Hamilton, Jason L. Brown, John Butcher, Lie, Loesche, Loesche, Marcello Riggio, Mark C. Butcher, Marsh, Marsh, McKee, Miller, Orstavik, Pratten, Russell, Shauna Culshaw, Sudo, Sudo, Tracy Young, William Johnston   +29 more
core   +3 more sources

A MXene‐Based Nanothermal Knife Inhibits Aggresome‐Mediated Persister Formation for Preventing Dental Caries

Advanced Science, Volume 12, Issue 33, September 4, 2025.
Early childhood caries (ECC) involves cariogenic persisters that evade antimicrobial treatment. Persisters achieve this by downregulating heat shock proteins (HSPs) and formation of protein aggregates. Ti3C2 MXene‐based photothermal therapy (PTT) acts as a “nanothermal knife,” disrupting membranes, upregulating HSPs, inhibits aggregates, prevents ...
Yinyin Zhang, Leilei Yang, Jing jiao, Wenshuai Li, Sen Lin, Xianlong Zong, Haoyang Qin, Danfeng Liu, Rui Li   +8 more
wiley   +1 more source

Supragingival Microbiota Alterations in Individuals With Sleep Bruxism: A Pilot Study

Journal of Oral Rehabilitation, Volume 52, Issue 9, Page 1319-1327, September 2025.
ABSTRACT Background Sleep bruxism (SB) is an oral behaviour associated to jaw clenching or grinding of the teeth. Its aetiology is most likely multifactorial; however, recent studies suggested that SB is associated with activation of the sympathetic nervous system. Dysbiosis of the oral microbiota is linked to oral and systemic diseases.
Athénaïs Collard, Alban Mathieu, Paolo Landa, Annik Pelletier, Gilles J. Lavigne, Arnaud Droit, Nelly Huynh, Vanessa P. Houde   +7 more
wiley   +1 more source

Growth Requirements of Streptococcus mitis and Sulfonamide Resistance.

Experimental Biology and Medicine, 1950
Summary1. Differences in the vitamin requirements of susceptible strains of S. mitis, their artificially-induced resistant variants and a naturally-resistant S. fecalis, have been determined. 2. The greatest difference was in the PGA requirements, the mitis strains grew in its absence; the resistant mutants required PGA. 3.
Virginia M. Harrison, William E. Clapper
openaire   +3 more sources