Genomic characterization of mobile genetic elements associated with antimicrobial resistance in <i>Streptococcus pneumoniae</i> from Australia. [PDF]
Sunmonu GT +5 more
europepmc +1 more source
In this graphical abstract, the transfer experiment of antimicrobial resistance genes and metagenomic analysis are presented, and they are the core components of relevant microbial research. ABSTRACT High‐throughput sequencing technology (HTST) can effectively analyze the sequence information in the DNA of samples and provide a comprehensive ...
Kexuan Wu +8 more
wiley +1 more source
<i>Pneumo</i>Wiki: a pan-genome-based database for the pathogen <i>Streptococcus pneumoniae</i>. [PDF]
Mehlan H +7 more
europepmc +1 more source
Shifting From Systemic to Precision‐Targeted Complement Therapies: Opportunities and Hurdles
Complement therapeutics have expanded considerably, but systemic inhibitors remain limited by infection risks, breakthrough events, and loss of physiological functions. Emerging targeted approaches aim for organ‐, tissue‐, or cell‐specific modulation of complement activity, potentially offering greater precision while reducing treatment burden and ...
Marco Mannes +2 more
wiley +1 more source
Immunoprophylactic potential against pneumonia caused by indigenous isolates of Klebsiella pneumoniae and Streptococcus pneumoniae in experimental mice. [PDF]
Waqar I +4 more
europepmc +1 more source
Achillea millefolium Linn., commonly known as yarrow, is an extraordinary medicinal plant. A. millefolium has broad therapeutic potential due to its phytochemistry and essential oil composition. It possesses pharmacological properties, including antidiabetic, antioxidant, anti‐inflammatory, liver‐protective, antimicrobial, and gastroprotective effects,
Tooba Majeed +14 more
wiley +1 more source
Streptococcus pneumoniae upregulates Toll2, Toll9, and defensin genes in Bombyx larvae infection model. [PDF]
Chowdhury FR +10 more
europepmc +1 more source
Abstract Patients with paroxysmal nocturnal hemoglobinuria (PNH) on anti‐C5 often experience extravascular hemolysis with anemia. Iptacopan, the first oral proximal complement inhibitor targeting factor B, has shown efficacy and safety in PNH patients. APPULSE‐PNH (NCT05630001), a phase 3b, single‑arm, open‐label trial, enrolled adult patients with PNH
Austin Kulasekararaj +31 more
wiley +1 more source
Genomic characterization of invasive disease-causing <i>Streptococcus pneumoniae</i> in Lebanon, 2003-2025. [PDF]
Dakroub F +19 more
europepmc +1 more source
Immunogenic insights and experimental validation of a multiepitope vaccine construct against <i>Streptococcus pneumoniae</i>. [PDF]
Devarakonda Y +3 more
europepmc +1 more source

