Results 141 to 150 of about 1,096,962 (313)

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Effect of post-weaning management practices on physiological and immunological responses of weaned beef calves [PDF]

, 2011
peer-reviewedThe objectives were: i) to investigate the physiological and immunological responses of previously grazed, abruptly weaned beef calves that were then either housed (H) and offered a diet of grass silage ad libitum plus concentrate or ...
Lynch, E.M., McGee, Mark, McGee, M., Lynch, Eilish M, Doyle, Sean, Earley, Bernadette, Earley, B.   +6 more
core  

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

The physiological and behavioural responses of sheep exposed to heat load within intensive sheep industries

, 2006
The live export and feedlotting industries are the major intensive sheep industries in Australia. During live shipment, sheep are exposed to prolonged periods of high heat and humidity, with little relief for several days, while environmental conditions ...
Stockman, Catherine Ann
core  

Impact of Teleworking on Work‐Related and Home‐Related Stress at During the First Global Lockdown–The International COVISTRESS Study

Brain and Behavior
Background The initial lockdown during the pandemic of COVID‐19 led to adjustments in working conditions, including extensive use of telecommuting whenever possible, putatively influencing both work‐related and home‐related stress. Objectives Our aim was
Sébastien Couarraze, Guillaume Decormeille, Louis Delamarre, Fouad Marhar, Karen Gbaglo, Raimundo Avilès Dorlhiac, Mickael Berthon, Andy Su‐I Liu, Samuel Antunes, Bruno Pereira, Julien S Baker, Morteza Charkhabi, Ukadike C Ugbolue, Reza Bagheri, José J. Gil‐Cosano, Marek Zak, The COVISTRESS Network, Maëlys Clinchamps, Frédéric Dutheil   +18 more
doaj   +1 more source

Investigation of the relationship between university students’ attentional impulsivity levels and psychological and physiological stress responses

Archives of Medical Science
Introduction The purpose of this study is to investigate the relationship between attentional impulsivity levels and physiological and psychological stress responses of university students.
Burcu Köksal
doaj   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Physiological and behavioural responses to fear and discomfort in dogs and goats [PDF]

, 2010
In this thesis, behavioural and physiological methods were combined to better understand reactions to fearful situations in dogs and separation in goats. Fear of gunshots is common in dogs, but also other fears, such as fear of walking on certain floors.
Winblad von Walter, Louise
core  

Exploring Physiological and Nonphysiological Responses of Sun-Induced Chlorophyll Fluorescence to Different Levels of Water Stress in Winter Wheat

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Sun-induced chlorophyll fluorescence (SIF) has recently been used for the early detection of plant stress. The response of SIF to water stress is complicated by the combination of physiological and nonphysiological dynamics in SIF variations and has not ...
Jingyu Lin, Litao Zhou, Jianjun Wu
doaj   +1 more source