Results 11 to 20 of about 5,385,784 (286)

The Role of Cortisol in Chronic Stress, Neurodegenerative Diseases, and Psychological Disorders

Cells, 2023
Cortisol, a critical glucocorticoid hormone produced by the adrenal glands, plays a pivotal role in various physiological processes. Its release is finely orchestrated by the suprachiasmatic nucleus, governing the circadian rhythm and activating the ...
Emilija Knezevic, Katarina Nenic, Vladislav Milanovic, N. Knezevic   +3 more
semanticscholar   +1 more source

The role of soluble epoxide hydrolase and its inhibitors in depression

Brain, Behavior, & Immunity - Health, 2021
Evidence suggests that around 30 ​% of patients with depression do not respond to antidepressant treatment, with most of them having sub-chronic levels of inflammation.
Alessandra Borsini
doaj   +1 more source

The Anti-Inflammatory Role of Omega-3 Polyunsaturated Fatty Acids Metabolites in Pre-Clinical Models of Psychiatric, Neurodegenerative, and Neurological Disorders

Frontiers in Psychiatry, 2020
Inflammation has been identified as one of the main pathophysiological mechanisms underlying neuropsychiatric and neurodegenerative disorders. Despite the role of inflammation in those conditions, there is still a lack of effective anti-inflammatory ...
Juliette Giacobbe, Bonnie Benoiton, Patricia Zunszain, Carmine M. Pariante, Alessandra Borsini   +4 more
doaj   +1 more source

Can (immune and other) gene expression help us to treat depression?

Brain, Behavior, & Immunity - Health, 2021
It is becoming clearer that it might be a combination of different biological processes such as genetic, environmental, and psychological factors, together with immune system, stress response, brain neuroplasticity and the regulation of neurotransmitters,
Nicole Mariani
doaj   +1 more source

Gene expression studies in Depression development and treatment: an overview of the underlying molecular mechanisms and biological processes to identify biomarkers

Translational Psychiatry, 2021
A combination of different risk factors, such as genetic, environmental and psychological factors, together with immune system, stress response, brain neuroplasticity and the regulation of neurotransmitters, is thought to lead to the development of major
Nicole Mariani, Nadia Cattane, Carmine Pariante, Annamaria Cattaneo   +3 more
doaj   +1 more source

Navigating a complex landscape – A review of the relationship between inflammation and childhood trauma and the potential roles in the expression of symptoms of depression

Brain, Behavior, & Immunity - Health, 2022
Recent research has explored associations between depression and inflammation, and interactions between childhood trauma and both factors. Major Depressive Disorder (MDD) is a prevalent issue and with one third of patients not responding to standard ...
Courtney Worrell
doaj   +1 more source

Immediate Psychological Responses and Associated Factors during the Initial Stage of the 2019 Coronavirus Disease (COVID-19) Epidemic among the General Population in China

International Journal of Environmental Research and Public Health, 2020
Background: The 2019 coronavirus disease (COVID-19) epidemic is a public health emergency of international concern and poses a challenge to psychological resilience.
Cuiyan Wang, R. Pan, X. Wan, Y. Tan, Linkang Xu, C. Ho, R. Ho   +6 more
semanticscholar   +1 more source

Psychological stress and performance [PDF]

, 2021
Psychological stress is inherent in sport, particularly at the higher levels of competition, and has implications for individuals’ well-being and performance. Athletes, coaches, officials, and parents alike are influential stakeholders in sport and each of these groups of individuals are likely to experience stress at some point during their own or ...
Didymus, F, Norris, L, Potts, A, Staff, H   +3 more
openaire   +1 more source

Depression, anxiety and stress symptoms in Brazilian university students during the COVID-19 pandemic: Predictors and association with life satisfaction, psychological well-being and coping strategies

PLoS ONE, 2021
Background The COVID-19 pandemic raises concerns about the mental health of the world population. Protection measures to prevention the disease impacted education and undergraduate students were exposed to additional stressors.
Adriana Rezende Lopes, O. K. Nihei
semanticscholar   +1 more source

An investigation into the relationship between social support, stress, and psychological well‐being in farmers

Journal of Community Psychology, 2022
This study investigated the stress‐buffering effect of social support on psychological well‐being and impact of demographic factors on stress in a sample of farmers.
A. Deegan, Simon Dunne
semanticscholar   +1 more source