Results 221 to 230 of about 6,221,933 (283)

Additional file 1 of Galectin-3 associates with NF-κB activation and mitochondrial redox–related protein signatures in catecholamine-induced stress cardiomyopathy

open access: green
Mana Kalani   +11 more
openalex   +1 more source

Emerging insights into amino acid metabolism in the heart: implications for cardiovascular diseases and therapeutic targeting

open access: yesBritish Journal of Pharmacology, EarlyView.
As a metabolically versatile organ, the heart is capable of generating energy from a wide range of substrates. Although fatty acid and glucose metabolism in the heart have been extensively studied, the contribution of amino acid metabolism to cardiac physiology and disease is gaining increasing attention.
Tayyiba Azam   +6 more
wiley   +1 more source

Mutual exclusive gene expression reveals a stress-induced compensatory role of taurine uptake in dilated cardiomyopathy [PDF]

open access: gold
Jinpu Cai   +19 more
openalex   +1 more source

Targeting CKIP‐1 for Disease Therapy: Cellular Functions, Molecular Networks, and Clinical Potential

open access: yesCell Proliferation, EarlyView.
CKIP‐1, as a scaffold protein with special structural domains, treats related diseases through multiple emerging targeted technologies.
Xin Huang   +4 more
wiley   +1 more source

MD‐1 Deficiency Mitigates Atherosclerosis by Inhibiting NLRP3 Inflammasome Activation via cGAS‐STING Dependent Pathway in Macrophages

open access: yesCell Proliferation, EarlyView.
MD‐1 is induced and activated in macrophages. The activated MD‐1 subsequently promotes the cGAS‐STING‐TBK1‐IRF3 signalling pathway to activate the NLRP3 inflammasome, and subsequently increases pro‐inflammatory macrophage polarisation and decreases plaque stability to accelerate the development of atherosclerosis.
Fang Zhao   +9 more
wiley   +1 more source

Inborn errors of immunity in children with neuroinflammation

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Abstract Inborn errors of immunity (IEIs), an expanding group of monogenic disorders with diverse clinical manifestations, are increasingly recognized to include neuroinflammatory disease. Examples of diseases included under this umbrella are Aicardi–Goutières syndrome, deficiency of adenosine deaminase 2, familial haemophagocytic lymphohistiocytosis ...
Eppie M Yiu   +5 more
wiley   +1 more source

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