Results 71 to 80 of about 6,111,093 (245)

Stress cardiomyopathy following antibiotic-induced anaphylaxis in a 16-month-old child

Annals of Pediatric Cardiology
Takotsubo cardiomyopathy (TTC) is a reversible stress-induced myocardial syndrome characterized by transient left ventricular (LV) dysfunction in the absence of coronary artery disease. Pediatric cases are rare, especially in infants and toddlers.
Mareddy Nikhila Reddy, Ramya Keerthy, Rajesh Babu Gudipati, Ravinder Reddy Lotkal   +3 more
doaj   +1 more source

SerpinA3 is an Endogenous TGF‐β Receptor Antagonist that Attenuates Cardiac Fibroblast Activation and Fibrotic Remodeling

Advanced Science, EarlyView.
SerpinA3 acts as an endogenous TGF‐β receptor antagonist that binds to the extracellular domain of TGFR‐1, thereby preventing TGFR‐1–TGFR‐2 complex formation. This receptor‐level blockade suppresses TGF‐β/Smad2/3 signaling, attenuates cardiac fibroblast activation, and extracellular matrix deposition, and ultimately alleviates pressure overload–induced
Hui Wang, Jieyu Cui, Chunlu Huang, Wanyi Guo, Tong Liu, Yi Zhu, Shuai Shao, Kangyin Chen, Jinlong He, Qiankun Bao   +9 more
wiley   +1 more source

Characterization of the Myocardial Inflammatory Response in Acute Stress-Induced (Takotsubo) Cardiomyopathy

JACC: Basic to Translational Science, 2018
Summary: Takotsubo cardiomyopathy is an acute stress-induced heart failure syndrome for which the exact pathogenic mechanisms are unclear, and consequently, no specific treatment exists.
Heather M. Wilson, BSc, PhD, Lesley Cheyne, BSc, Paul A.J. Brown, MBChB, PhD, Keith Kerr, MBChB, Andrew Hannah, MBChB, Janaki Srinivasan, RDCS, Natallia Duniak, MBChB, Graham Horgan, BA, MSc, PhD, Dana K. Dawson, DM, DPhil   +8 more
doaj   +1 more source

Periostin‐CCL3 Feedforward Signaling Loop Promotes Cardiac Fibrosis and Cardiomyocyte Necroptosis in Arrhythmogenic Cardiomyopathy

Advanced Science, EarlyView.
POSTN‐CCL3 signaling forms a feed‐forward circuit between cardiomyocytes and cardiac myofibroblasts in arrhythmogenic cardiomyopathy. POSTN activates JNK/RIP3‐dependent necroptotic signaling and JNK/ETS2‐induced CCL3 expression in cardiomyocytes. In turn, CCL3‐CCR5 signaling in cardiac myofibroblasts activates NF‐κB/p65 and promotes POSTN expression ...
Tiantian Wu, Ruotong Li, Xiaoyue Zhang, Dandan Chen, Jianmeng Yang, Mengmeng Li, Yuhan Yin, Ya Wang, Yuqiu Tian, Haoling Yan, Dan Cui, Jiangping Song, Gaoliang Ouyang   +12 more
wiley   +1 more source

CLINICAL CASE OF STRESS-INDUCED CARDIOMYOPATHY

Кардиоваскулярная терапия и профилактика, 2014
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A. G. Syrkina, V. A. Stolyarov, N. V. Belokopytova, V. A. Markov   +3 more
doaj   +1 more source

Stress-induced cardiomyopathy complicating severe babesiosis [PDF]

, 2011
A post-menopausal lady with severe babesiosis developed a basal-type stress-induced cardiomyopathy. Left ventricular function normalized at three months.
Okon, Emmanuel, Dodson, John, Vorobiof, Gabriel, Odigie-Okon, Esosa; Department of Medicine, Yale University (Bridgeport Hospital), Bridgeport, CT, USA   +3 more
core  

Lactate Signal: Modulator of Cellular Energy Production and Anabolism

Advanced Science, EarlyView.
Compartmentalized lactate signaling provides a spatial framework for understanding how lactate‐rich states are generated, transported, sensed, and translated into biological outputs. This Review integrates extracellular, cytosolic, mitochondrial‐associated, and nuclear lactate mechanisms to explain how lactate shapes metabolic adaptation, immune ...
Han Wang, Si‐Yuan Yang, Wei Xu
wiley   +1 more source

Takotsubo cardiomyopathy: etiology, diagnosis, and optimal management

Research Reports in Clinical Cardiology, 2014
Siu-Hin Wan, Jackson J Liang Department of Internal Medicine, Mayo Clinic and Foundation, Rochester, MN, USA Abstract: Takotsubo cardiomyopathy, also known as stress-induced cardiomyopathy or apical ballooning syndrome, is a condition of stress-induced ...
Wan SH, Liang JJ
doaj  

Ultrasound‐Triggered piRNA Delivery Using Biomimetic Phase‐Changeable Nanoparticles for Theranostics of Myocardial Infarction

Advanced Science, EarlyView.
A biomimetic ultrasound‐responsive piRNA delivery nanoparticle platform (piR‐NPs) enables targeted delivery and ultrasound (US)‐triggered release of piR‐1873 in infarcted myocardium. The released piR‐1873 suppresses Usp2‐mediated RIP1/RIP3/MLKL necroptosis, reduces myocardial injury and fibrosis, and promotes cardiac functional recovery, providing a ...
Yajun Zhang, Hongzhao Qi, Yanyan Yang, Feng Wang, Tiantian Han, Yanbei Lei, Xiaolu Li, Zhibin Wang, Hua Qu, Tao Yu, Pin Sun   +10 more
wiley   +1 more source

Human Engineered Heart Tissues Reproduce Trigger‐ and Substrate‐Driven Mechanisms of Ventricular Tachycardia

Advanced Science, EarlyView.
Engineered heart tissues (EHTs) derived from human iPSCs replicate mechanisms of ventricular tachycardia at the tissue level. Acquired Long‐QT conditions cause early afterdepolarizations, wavebreak, and transient rotors; in contrast, focal cryoinjury forms a stable substrate that supports ongoing reentry.
Matthew Fiedler, Alejandra Vasquez Limeta, Ernesto Reyes Sanchez, Leah Carter, Francisco Altamirano   +4 more
wiley   +1 more source