Results 181 to 190 of about 37,299 (258)

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Timed exercise modulates inter-coupling strength between evening and morning oscillators in mice. [PDF]

NPJ Biol Timing Sleep
Miyagi N, Matsuura N, Yamanaka Y.
europepmc   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Planned Fibular Osteotomy as a Method of Biological Dynamization in the Staged Damage-Control Management of a Fraser Type I Floating Knee. [PDF]

J Orthop Case Rep
Jeff Walter Rajadurai OR, Purushothaman K, Kumar MS, Kanchan N, Kanna PD, Abraham A.   +5 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Pandemic-related stressors and social resources differentially predict competence and problem behavior trajectories of young children born during the pandemic. [PDF]

Child Dev
Gray SAO, Mulligan DJ, Carter AS, McCarthy K, Goldstein B, Drury SS, Grasso DJ, Briggs-Gowan MJ.   +7 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Effect of Low-Load, Long-Duration Stretching on Pain and Mobility in Sacroiliac Joint Dysfunction. [PDF]

Cureus
Patel SJ, Shinde S, Thomas MS, Ambali MP, Kale HY.   +4 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Chronic time pressure as a predictor of symptoms of depression, anxiety and stress. [PDF]

BMC Psychol
Ogden R, Schoetensack C, Klegr T, Pestana JV, Valenzuela R, Goncikowska K, Giner-Domínguez G, Papastamatelou J, Chappuis S, Boente MF, Meteier Q, Černohorská V, Codina N, Martin-Söelch C, Wittmann M, Witowska J.   +15 more
europepmc   +1 more source