Results 241 to 250 of about 38,947 (304)

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Plant-Based vs. Omnivore diets for athletic performance outcomes among recreational athletes in university dining halls: a randomized crossover study. [PDF]

Nutr J
Raygoza C, Roberts A, Guidetti A, Cai O, Sangowdar P, Muriuki EN, Laverick-Johnson H, Sanguinetti G, Smith E, Fammartino A, Robinson J, Lee E, Policastro P, Mills C, Kuhnle G, Svennevik E, Gardner C.   +16 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Biopsychosocial Factors Affecting Disability in Individuals with Chronic Nonspecific Low Back Pain: A Cross-Sectional Study. [PDF]

J Pain Res
Canli İ, Özüdoğru A.
europepmc   +1 more source

Differential benefits of 12-week morning vs. evening aerobic exercise on sleep and cardiometabolic health: a randomized controlled trial. [PDF]

Sci Rep
Shen B, Zheng H, Liu H, Chen L, Yang G.
europepmc   +1 more source

The long walk to a short half-life: the discovery of augmented renal clearance and its impact on antibiotic dosing. [PDF]

J Antimicrob Chemother
Lipman J, Lewis RE.
europepmc   +1 more source

Circadian Rhythm Dysfunction in Neurodegenerative Diseases: A Bidirectional Perspective and Therapeutic Potential. [PDF]

Nat Sci Sleep
Namgyal D, Lim CS.
europepmc   +1 more source

Measuring cortisol in Cushing syndrome: diagnosis, monitoring, and cortisol circadian rhythm improvement.

J Clin Endocrinol Metab
Hamidi O, St-Jean M, Lacroix A, Bancos I.   +3 more
europepmc   +1 more source