Results 51 to 60 of about 38,164 (261)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Modeling Long and Short-term prosody for language identification [PDF]
, 2005 International audienceThis paper addresses the problem of modeling prosody for language identification. The main goal is to validate (or invalidate) some languages characteristics proposed by the linguists by the mean of an automatic language ...
Rouas, Jean-Luc
core +4 more sources
Micronutrients against oxidative stress - time for clinical recommendations? [PDF]
Critical Care, 2012 Antioxidant micronutrient supplementation may be beneficial for critically ill patients. Often, cocktails of antioxidant micronutrients are used. Consequently, meta-analyses of available randomized controlled trials of antioxidant micronutrient supplementation are of particular interest.
openaire +2 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Lexical stress constrains English-learning infants' segmentation in a non-native language. [PDF]
, 2018 Infants' ability to segment words in fluent speech is affected by their language experience. In this study we investigated the conditions under which infants can segment words in a non-native language.
Mateu, Victoria E, Sundara, Megha
core
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Pauses and the temporal structure of speech [PDF]
, 1994 Natural-sounding speech synthesis requires close control over the temporal structure of the speech flow. This includes a full predictive scheme for the durational structure and in particuliar the prolongation of final syllables of lexemes as well as for ...
Zellner, Brigitte
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Language identification with suprasegmental cues: A study based on speech resynthesis [PDF]
, 1999 This paper proposes a new experimental paradigm to explore the discriminability of languages, a question which is crucial to the child born in a bilingual environment.
Mehler, Jacques, Ramus, Franck
core
Syllable, accent, rhythm: typological and methodological considerations for teaching Spanish as a foreign language [PDF]
, 2012 El ritmo es una propiedad del habla relacionada con la organizacióntemporal de los sonidos en términos de agrupamiento. Las unidades desegmentación son específicas de cada lengua y emergen de propiedades fonológicastales como la estructura silábica, la ...
Lahoz, José
core +2 more sources