Results 61 to 70 of about 38,164 (261)

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Letter to Sound Rules for Accented Lexicon Compression [PDF]

open access: yes, 1998
This paper presents trainable methods for generating letter to sound rules from a given lexicon for use in pronouncing out-of-vocabulary words and as a method for lexicon compression.
Black, A., Lenzo, K., Pagel, V.
core   +2 more sources

Oxytocin release in stressful times

open access: yesPsychoneuroendocrinology, 2022
Duque-Wilckens, Natalia   +1 more
openaire   +3 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Rhythm in Korean verse, sico [PDF]

open access: yes, 2015
Although rhythm in language and speech is elusive, the prosodic pattern in verse and the way language is aligned to music can reveal cross-linguistic differences in rhythm.
Jeon, Hae-Sung
core  

Stress-timing and syllable-timing reanalyzed

open access: yesJournal of Phonetics, 1983
Abstract: Comparisons of data from continuous texts in English, Thai, Spanish, Italian and Greek, show that interstress intervals in English, a stress-timed language, are no more isochronous than interstress intervals in Spanish, a syllable-timed language, or any of the other languages investigated.
openaire   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Finding Unexpected Contentment in Stressful Times

open access: yesJournal of Teaching and Learning with Technology, 2021
The COVID-19 pandemic has created a vast array of challenges and some benefits that must not be overlooked.  Describing the experience of teaching with social anxiety and pulling upon pedagogy about caring instructors, this reflective essay explains how teaching through the pandemic lead to the author finding enjoyment in teaching.
openaire   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

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