Results 201 to 210 of about 10,727,912 (338)

Biomechanical Evaluation of Framework Materials in All-on-Four Versus All-on-Six Prostheses: A Finite Element Study. [PDF]

Clin Exp Dent Res
Cabbarova L, Tunçdemir AR, Mohammadi R.
europepmc   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Psychological Adjustment and Tolerance for Psychological Pain: A Chain Mediation Model of Stress Mindset and Perceived Stress. [PDF]

Behav Sci (Basel)
Çelik M, Batmaz H, Türk N, Derin S.
europepmc   +1 more source

OsCYP71D8L as a key regulator involved in growth and stress response by mediating gibberellins homeostasis in rice [PDF]

, 2019
Jiahao Zhou, Zeyu Li, Guiqing Xiao, Mingjuan Zhai, Xiaowu Pan, Rongfeng Huang, Haiwen Zhang   +6 more
openalex   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

From Perception to Adaptation: A Comparative Study of Plant Regulatory Networks in Response to Heat and Waterlogging Stress. [PDF]

Plants (Basel)
Iqbal J, Amanullah S, Li C, Qin X, Yu P, Chen X, Qiu D.   +6 more
europepmc   +1 more source

Transplantation of bone marrow mesenchymal stem cells decreases oxidative stress, apoptosis, and hippocampal damage in brain of a spontaneous stroke model

, 2014
Michele Longoni Calió, Darci Sousa Marinho, Gui Mi Ko, Renata Rodrigues Ribeiro, Adriana Aparecida Ferraz Carbonel, Lila Missae Oyama, Milene Subtil Ormanji, Tatiana Pinoti Guirao, Pedro Luiz Calió, Luciana Aparecida Reis, Manuel de Jesus Simões, Telma Lisbôa-Nascimento, Alice T. Ferreira, Clélia Rejane Antônio Bertoncini   +13 more
openalex   +1 more source

Effects of stress tensor fluctuations upon focusing [PDF]

, 2004
J. Borgman, L. H. Ford
openalex   +1 more source

Polymerization shrinkage and shrinkage stress development in ultra-rapid photo-polymerized bulk fill resin composites

, 2021
Hamad Algamaiah, Nick Silikas, David C. Watts   +2 more
openalex   +2 more sources