Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Validation of the Finnish Translation of the Acceptance and Action Questionnaire-II Among Finnish Mental Health Professionals. [PDF]
Keinonen K +4 more
europepmc +1 more source
Response of the Anaerobic Methanotroph “ Candidatus Methanoperedens nitroreducens” to Oxygen Stress [PDF]
Simon Guerrero-Cruz +6 more
openalex +1 more source
Trace elements and oxidative stress status in patients with psoriasis [PDF]
Adnan Kirmit +5 more
openalex +1 more source
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Relationship Between Perceived Stress and Anxiety in High School Senior Students: The Mediating Role of Social Support and the Moderating Influence of Lifestyle. [PDF]
Malinauskiene V, Malinauskas R.
europepmc +1 more source
Extracellular Cyclophilin A, Especially Acetylated, Causes Pulmonary Hypertension by Stimulating Endothelial Apoptosis, Redox Stress, and Inflammation [PDF]
Chao Xue +2 more
openalex +1 more source
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Academic stress through salivary biomarkers: A multivariate exploration of cortisol, IL-1β, CRP, and IgA levels with sex-specific insights. [PDF]
Castillo-Klagges R +4 more
europepmc +1 more source

