Results 61 to 70 of about 3,288,287 (219)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Micro/nanoplastics pollution: emerging challenges for aquatic animals and food crops

Frontiers in Toxicology
Recent reports from worldwide reveal that micro/nanoplastics (MNPs) are pervasive pollutants affecting all ecosystems and a wide range of organisms, including animals, plants, fish, humans, and microorganisms.
Shrutarshee Kundu, Neeraj Kumar, Paritosh Kumar, Basavaraj PS, Ajay Kumar Singh, Dipti Godse, Kotha Sammi Reddy   +6 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Effect of artificial and natural diets on the morphometrics and biology of Sesamia inferens (Walker) (Lepidoptera: Noctuidae)

Journal of Basic and Applied Zoology
Background Sesamia inferens is a polyphagous pest severely impacting gramineous crops (e.g., rice, wheat, maize) across Asia, causing "dead heart" and "white ear" damage.
M. Chethankumar, Mallikarjuna Jeer, K. C. Sharma, Yogesh Yele   +3 more
doaj   +1 more source

Epithelial-to-Mesenchymal Transition in Pancreatic Adenocarcinoma

The Scientific World Journal, 2010
Epithelial to mesenchymal transition (EMT) is a physiologic process that allows morphological and genetic changes of carcinoma cells from an epithelial to a mesenchymal phenotype, which is the basis of the high metastatic potential of pancreatic cancer ...
Carla Cano, Yoshiharu Motoo, Juan L. Iovanna   +2 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

A parallel investigation of trauma exposure, maladaptive appraisals and posttraumatic stress reactions in two groups of trauma-exposed adolescents

European Journal of Psychotraumatology
Background: Maladaptive appraisals, such as thoughts about experiencing a permanent and disturbing change and about being a fragile person in a scary world, are associated with posttraumatic stress reactions (PTSR) for trauma-exposed children and ...
Andrea Undset, Tine K. Jensen, Grete Dyb, Tore Wentzel-Larsen, Silje M. Ormhaug, Synne Stensland, Ines Blix   +6 more
doaj   +1 more source

Does work-personal life interference predict turnover among male and female managers, and do depressive symptoms mediate the association? A longitudinal study based on a Swedish cohort

BMC Public Health, 2018
Background In the present study we used a longitudinal design to examine if work-personal life interference predicted managerial turnover, if depressive symptoms mediated the association, and if the relationships differed by gender.
Anna Nyberg, Paraskevi Peristera, Claudia Bernhard-Oettel, Constanze Leineweber   +3 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Root growth, yield and stress tolerance of soybean to transient waterlogging under different climatic regimes

Scientific Reports
Global warming-induced abiotic stresses, such as waterlogging, significantly threaten crop yields. Increased rainfall intensity in recent years has exacerbated waterlogging severity, especially in lowlands and heavy soils.
Vinay M. Gangana Gowdra, B. S. Lalitha, Hanamant M. Halli, E. Senthamil, Priyanka Negi, H. M. Jayadeva, P. S. Basavaraj, C. B. Harisha, K. M. Boraiah, Sandeep B. Adavi, P. G. Suresha, Raghavendra Nargund, Ganesh Mohite, K. Sammi Reddy   +13 more
doaj   +1 more source