Results 121 to 130 of about 6,447,976 (288)
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
Spartan Release Engagement Mechanism (REM) stress and fracture analysis [PDF]
The revised stress and fracture analysis of the Spartan REM hardware for current load conditions and mass properties is presented. The stress analysis was performed using a NASTRAN math model of the Spartan REM adapter, base, and payload.
Marlowe, D. S., West, E. J.
core +1 more source
Dynamic Stress Analysis with Different boundry Conditions by ISO-Surface behaviour [PDF]
, 2015 Any CAE (Computer Aided Engineering) software the first result will be in contour manner which comes with the colour scale (Legend).But that will only give rough scenario about what is happening inside the layers in object when force is applied.
Pandya, P. K. (Parth) +1 more
core
Molecular Oncology, EarlyView.Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser +14 more
wiley +1 more source
Wind stress and its dependence on wind speed and sea state [PDF]
, 1992 The aim of the project is to detect and quantify the effect of sea state on the wind stress. An overview of the basic theory of wind stress in the surface layer is provided, along with a more detailed description of the inertial dissipation method which ...
Yelland, M.J.
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Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
HUBUNGAN ANTARA STRES DAN PEMBELIAN IMPULSIF PADA KALANGAN PEREMPUAN REMAJA AKHIR [PDF]
The many demands or obligations that must be carried out in late adolescence often cause stress in individuals, both academic stress and stress due to obligations or other demands.
Rusmita, Shinta Eka
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Analysis of thermal stress and metal movement during welding [PDF]
, 1972 Objectives of study were: investigation of temperature changes caused by welding arc with analysis of temperature distribution; development of system of mathematical statements describing thermal stresses and plastic strains during welding; and ...
Andrews, J. B., Masubuchi, K.
core +1 more source
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source