Results 11 to 20 of about 6,427,335 (253)

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

At Ease with Your Warnings: The Principles of the Salutogenesis Model Applied to Automatic Static Analysis [PDF]

, 2016
The results of an automatic static analysis run can be overwhelming, especially for beginners. The overflow of information and the resulting need for many decisions is mentally tiring and can cause stress symptoms. There are several models in health care
Ostberg, Jan-Peter, Wagner, Stefan
core   +2 more sources

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait, R. Al‐Saadi, A. Lopez‐Cortes, K. Dzhuma, M. Oostveen, J. Brok, S. Irtan, M. Weeks, J. Bate, S. Baker, R. Williams, M. Powis, D. Saunders, O. Olsen, T. Watson, S. Shelmerdine, S. Vaidya, L. Howell, C. Duncan, G. M. Vujanic, C. Stiller, G. P. Balchin, T. Chowdhury, K. Pritchard‐Jones   +23 more
wiley   +1 more source

Stress Analysis [PDF]

, 1988
The following types of forces contribute to the stresses in a Dolos in a pack exposed to waves:1)Gravity forcesCompaction forces (mainly due to settlements, gravity and flow forces)2) Flow forces3) Impact forces (impacts between moving concrete blocks)
openaire   +2 more sources

Pneumococcal Gene Complex Involved in Resistance to Extracellular Oxidative Stress [PDF]

, 2012
Streptococcus pneumoniae is a Gram-positive bacterium which is a member of the normal human nasopharyngeal flora but can also cause serious disease such as pneumonia, bacteremia, and meningitis. Throughout its life cycle, S.
Anne de Jong, Barbuti, Battig, Bijlsma, Bogaert, Bortoni, Braun, Brot, Bus, Carlos J. Orihuela, Cecilia A. Hinojosa, Chae, Chen, de Ruyter, Dopazo, Duane, Even, Falord, Haasum, Hendriksen, Hiller, Hirst, Holmgren, Holmgren, Hoshi, Hoskins, Ibrahim, Imlay, Imlay, J. N. Weiser, Jetta J. E. Bijlsma, Kadioglu, Kim, Kloosterman, Kloosterman, Kuipers, Lau, Liu, Liu, Liu, Marchler-Bauer, Margolis, Martner, Matthias, McAllister, Miller, Neef, Novak, Obert, Orihuela, Oscar P. Kuipers, Park, Parra-Lopez, Paterson, Pearce, Pericone, Pericone, Pericone, Pesakhov, Petit, Potter, Ramos-Montanez, Regev-Yochay, Robertson, Rosen, Schaper, Skaar, Spellerberg, Sun, Terzaghi, Tettelin, Tseng, Vahid Farshchi Andisi, Yesilkaya, Ziegelhoffer, Zweers   +75 more
core   +4 more sources

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

A stress free model for residual stress assessment using thermoelastic stress analysis [PDF]

, 2014
Thermoelastic Stress Analysis (TSA) has been proposed as a method of obtaining residual stresses. The results of a preliminary study demonstrated that when Al-2024 plate containing holes that were plastically deformed by cold expansion process to 2% and ...
Achintha, Mithila, Dulieu-Barton, Janice, Howell, Geoff, Robinson, Andy   +3 more
core   +1 more source

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman, Tadi Hondonga, Alison Berry, Caitlin Elgarten, Jason Freedman, Katelyn Oranges, Sara McDonough, Caroline Diorio, L. Lee Dupuis   +8 more
wiley   +1 more source

High temperature stress-strain analysis [PDF]

, 1984
The objectives are threefold: to assist in developing predictive tools needed to improve design analyses and procedures for the efficient and accurate prediction of burner liner structural performance and response; to calibrate, validate, and evaluate ...
Thompson, R. L.
core   +2 more sources