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Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

open access: yesFEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi   +7 more
wiley   +1 more source
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Stress Analysis (Direct Stresses)

1990
In Programme 3 we saw how external loads on a pin jointed frame structure induced axial forces in the individual members of the frame. In Programme 4 we saw how external loads induced shearing forces and bending moments in beams. We now begin to look more closely at the way in which the material of which the structure is made reacts to the effect of ...
Jack Cain, Ray Hulse
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Stress Analysis

SAE Technical Paper Series, 1982
<div class="htmlview paragraph">The basic concepts of elastic and inelastic behavior are presented. The elevation of stresses at notches, the stress concentration factor, K<sub>t</sub> and fatigue notch factor, K<sub>f</sub>, and sources of differences between K<sub>t</sub> and K<sub>f</sub> are ...
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