Results 41 to 50 of about 916,884 (347)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
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Entropy, 2019 The plastic deformation of bulk metallic glasses (BMGs) depends significantly on applied stress states, and more importantly, in practical applications of BMGs as structural materials, they always deform under complex stress fields.
Shunhua Chen +3 more
doaj +1 more source
Research on the deformation of a confined aquifer based on Cosserat continuum mechanics [PDF]
Proceedings of the International Association of Hydrological Sciences, 2015 Recent monitoring of land subsidence and soil deformation indicates a new phenomenon where excessive and continuous deformation occurs in the sandy aquifers in Shanghai and the Su-Xi-Chang region of China. It is hard to explain factors contributing to
Y. S. Xu, N. Zhang, Y. Yuan, S. L. Shen
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Mechanical and microscopic properties of the reversible plastic regime in a 2D jammed material [PDF]
, 2013 At the microscopic level, plastic flow of a jammed, disordered material consists of a series of particle rearrangements that cannot be reversed by subsequent deformation. An infinitesimal deformation of the same material has no rearrangements.
Arratia, Paulo E., Keim, Nathan C.
core +3 more sources
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
FEBS Open Bio, EarlyView.Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
Advances in Materials Science and Engineering, 2017 This paper presents the results of a laboratory experiment that aimed to characterize the permanent deformation behavior of coarse grained soils. To evaluate the effects of the cyclic stress amplitude, initial mean stress, and initial stress ratio on the
Xianzhang Ling +5 more
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High-temperature mechanical behavior of polycrystalline yttrium-doped barium cerate perovskite [PDF]
, 2011 The high-temperature mechanical properties of the mixed ionic-electronic conductor perovskite BaCe0.95Y0.05O3-δ with average grain size of 0.40μm have been studied in compression between 1100 and 1300°C in air at different initial strain rates.
Jiménez Melendo, Manuel +4 more
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Intercompartmental communication in senescence
FEBS Open Bio, EarlyView.Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz +3 more
wiley +1 more source