Results 71 to 80 of about 747,078 (262)

Novel approaches to glaucomatous neurodegeneration, based on the integrated stress response

open access: yesMolecular Therapy: Nucleic Acids, 2023
Luciana B. Chiarini   +2 more
doaj   +1 more source

Challenges and Future Perspectives of Multi-/Hyperspectral Thermal Infrared Remote Sensing for Crop Water-Stress Detection: A Review

open access: yesRemote Sensing, 2019
Thermal infrared (TIR) multi-/hyperspectral and sun-induced fluorescence (SIF) approaches together with classic solar-reflective (visible, near-, and shortwave infrared reflectance (VNIR)/SWIR) hyperspectral remote sensing form the latest state-of-the ...
Max Gerhards   +3 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Optimized EEG-Based Stress Detection: A Novel Approach

open access: yesBiomedical and Pharmacology Journal
Mental stress from tight deadlines and financial worries often causes both mental and physical health issues, affecting productivity and decision-making. This study aims to improve stress detection by analyzing EEG signals, which provide a cost-effective, non-invasive method for tracking brain activity.
Sangita Ajit Patil, Ajay N. Paithane
openaire   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Modeling of human physiological stresses: A thermodynamics-based approach

open access: yesOccupational Ergonomics, 2006
This paper discusses thermodynamic basis for quantifying human physiological stresses. The deterministic nature of the second law of thermodynamics (entropy approach) and classical Maxwell relations were used to develop formulas to quantify human stress due to the artifact-human interactions.
Boregowda, Satish C.   +1 more
openaire   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Modeling and simulation of residual stress in metal cutting process: A review

open access: yesAdvances in Mechanical Engineering
Due to the complexity of analyzing residual stress, which involves numerous cutting parameters encompassing both mechanical and thermal stresses, various modeling and simulation methods, including analytical, numerical, and machine learning approaches ...
Ruihu Zhou
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Oxidative stress in cancer: from tumor and microenvironment remodeling to therapeutic frontiers

open access: yesMolecular Cancer
Oxidative stress is a pathological condition of redox signaling dysregulation and macromolecular oxidative damage arising from elevated ROS levels. Oxidative stress interacts with tumor cell growth regulation and tumor microenvironment remodeling, and ...
Xisong Liang   +8 more
doaj   +1 more source

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