Results 111 to 120 of about 10,094,478 (315)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
U.S. National Climate Change Assessment
, 2014 The report summarizes the science of climate change and the impacts of climate change in the United States, now and in the ...
Yohe, Gary W. +3 more
core
Anthropogenic climate change drives rising global heat stress and its spatial inequality
Nature CommunicationsGlobal heat stress is intensifying under climate change, yet the relative roles of natural and anthropogenic forcing remain insufficiently quantified.
Jian Peng +5 more
doaj +1 more source
Occupational stress, burnout, and change fatigue as predictors of quiet quitting among teachers
Acta PsychologicaThis study investigated the effects of occupational stress, burnout, and change fatigue on quiet quitting among teachers. The study adopted a cross-sectional design and hierarchical regression analysis. The sample was reached through convenience sampling
Ümit Dilekçi +2 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Challenging and changing stress-producing thinking
Western Journal of Medicine, 2001 “Your patient had a severe adverse reaction to the medication you prescribed.” Receiving this information, you as the patient's physician are flooded with negative thoughts and feelings and a desire to escape. Through selection, training, and reinforcement, you have been conditioned to think, “I must be thoroughly competent,” “I cannot make mistakes ...
openaire +3 more sources
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Drought including both meteorological drought and water deficiency stress conditions is a major constraint on global agricultural productivity, particularly affecting Brassica species, which are vital oilseed and vegetable crops.
Lord Abbey +2 more
core +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Abiotic Stress Effects on Plants under Climate Change
International Journal of Bio-Resource and Stress Management, 2017 Abiotic stress is a stress that occurs as a result of damage done to plants by non-living and often tangible factors such as intense sunlight, wind etc.
Subodh Kr. Bishnoi +3 more
doaj