Results 241 to 250 of about 10,094,478 (315)

Routine Online Psychological Therapy in an Insurance-Based Care Setting: Retrospective Service Evaluation of Real-World Outcomes. [PDF]

JMIR Form Res
Opsahl T, Meinert M, Brødsgaard E.
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

How the Acute Psychosocial Stress Response Ends: A Post-Stressor Transition Model of Glucocorticoid Feedback, Vagal Re-Engagement, and Frontolimbic Context Updating. [PDF]

Int J Mol Sci
Liu C, Zheng R, Wu Y, Zhang M.
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Stroke-Heart Syndrome: Mechanisms, Temporal Phenotypes, and Diagnostic Reasoning. [PDF]

Adv Sci (Weinh)
Lin F, Lyu J, Liu Y, Feng Z, Bao J, Song W, Zhu B, Liu M, Xue J, Weng J, Zhang J, Zhao J, Chen X, Dong B.   +13 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Variation and adaptation in the mechanical properties of primate molar tooth enamel. [PDF]

R Soc Open Sci
Foster FR, Mann AB, Constantino PJ, Scott RS.   +3 more
europepmc   +1 more source

Intensive Interventions for Burnout, Stress and Occupational Well-Being: A Critical Review and a Delivery-Format Framework. [PDF]

J Clin Med
Novak AM, Lev-Ari S.
europepmc   +1 more source