Advanced Materials Technologies, EarlyView.Scalable manufacturing challenges and limited potency remain two of the most intransigent issues limiting clinical translation of EV therapeutics. Mechanical cues can induce phenotypic changes and increased vesiculation in EV source cells without the use of extraneous reagents, chemicals, and/or cargo, thereby potentially drastically improving the ...
Emily H. Powsner +10 more
wiley +1 more source
<i>KCNV2</i>-Deficient Retinal Organoid Model of Cone Dystrophy-In Vitro Screening for AAV Gene Replacement Therapy. [PDF]
Int J Mol SciBusson SL +11 more
europepmc +1 more source
Fabrication, Properties, and Applications of Scaffolds for Bone Tissue Regeneration
Advanced Materials Technologies, EarlyView.This review explores cutting‐edge biomaterials and fabrication techniques for scaffolds in bone tissue regeneration. It conducts a critical comparison of various strategies, meticulously analyzes the key contradictions in the field, and outlines an integrated development path spanning from biomaterial selection to clinical application, while ...
Shangsi Chen, Min Wang
wiley +1 more source
Effects of NGR1 on the Protective Efficacy and Functional Vision Profile of Retinal Photodamage. [PDF]
Int J Med SciChang CH +9 more
europepmc +1 more source
Anti‐Slip Material‐Based Strategies and Approaches
Advanced Materials Technologies, EarlyView.This review highlights the principle mechanisms of slipping at the microscale, linking contact mechanics with a friction behavior model for surface interfaces. Main strategies to develop anti‐slip properties to the surfaces are discussed alongside standardized testing approaches.
Sogand Abbaspoor‐Zanjani +3 more
wiley +1 more source
Effect of Internal Structural Design on Stress Distribution in 3D-Printed Subperiosteal Implants Under Mechanical Loading. [PDF]
Bioengineering (Basel)Vörös Á +3 more
europepmc +1 more source
Ductility Tuning via Cluster Network Characteristics of Porous Components
Advanced Materials Technologies, EarlyView.Network optimization via cluster characteristics induced by interaction of stress concentration is proposed, demonstrating increased cluster size and dispersion in non‐uniform porous components. The optimized structures exhibit, for the first time, that enhanced ductility and damage progression is controllable through zigzag cluster network designed by
Ryota Toyoba +4 more
wiley +1 more source
Ciliary Defects in Inherited Retinal Diseases. [PDF]
Adv Genet (Hoboken)Guo G, Li L, Zhou J, Ran J.
europepmc +1 more source
Advanced Materials Technologies, EarlyView.This work establishes a framework for high‐resolution printed interconnects by coupling e‐jet printing control, multilayer deposition, and sintering optimization. Ink properties and printing speed influence particle stacking, while different sintering atmospheres drive distinct microstructural evolution.
Kaifan Yue +6 more
wiley +1 more source
Biomechanical and clinical evaluation of 3D-printed integrated tibial prosthesis for reconstructing AORI type Ⅲ tibial plateau defects. [PDF]
Front Bioeng BiotechnolWang Y, Zhou X, Guo L.
europepmc +1 more source