Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization
This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin +11 more
wiley +1 more source
Architects of the Developing Brain: Cytoskeleton-Organizing Molecules in Neurodevelopmental Disorders. [PDF]
Achkasova KA +5 more
europepmc +1 more source
Fiber energy harvesters offer unprecedented flexibility and a unique capacity for integration into commercial textiles, overcoming the limitations of bulky and rigid conventional devices. This review summarizes recent advances in fiber‐based energy harvesting and provides strategic outlooks to accelerate technological progress in the field. ABSTRACT As
Hanhwi Jang +8 more
wiley +1 more source
Retinal Impairments in Mice Lacking Both Nxnl1 and Nxnl2 Genes. [PDF]
Li Z +7 more
europepmc +1 more source
Development and evaluation of clove oil nanoemulsion-based topical cream for anti-inflammatory activity in mice. [PDF]
Shafiq A +4 more
europepmc +1 more source
Biomechanical evaluation of asymmetric metaphyseal cone applications for lateral tibial plateau fractures : a finite element study. [PDF]
Ren Y, Scott CEH, Xie S, Pankaj P.
europepmc +1 more source
Fraction of sex-inducing substances facilitates growth and body shape change in a Fasciola hepatica/gigantica hybrid: A novel in vitro research platform for studying liver-stage juveniles derived from mice. [PDF]
Ohno S +9 more
europepmc +1 more source
Crosstalk Between R-Loops, RNA/DNA Modifications, and Cell Death Dynamics in Canine Models of Retinitis Pigmentosa. [PDF]
Appelbaum T +4 more
europepmc +1 more source
A Dissolving Microneedle Design for Poorly Water-Soluble Drugs for Enhanced Skin Permeation and Transdermal Delivery Fabricated Using 3D Printing. [PDF]
Jin SG.
europepmc +1 more source

